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Prolonged Loss of Oxidative Phosphorylation and Mitochondrial Mass Characterize CD66b+ Leukocytes from Patients with Sepsis.

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Title: Prolonged Loss of Oxidative Phosphorylation and Mitochondrial Mass Characterize CD66b+ Leukocytes from Patients with Sepsis.
Authors: Rodhouse C; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Barrios EL; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Zeumer-Spataro L; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Balzano-Nogueira L; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA., Wu R; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.; Department of Biostatistics, University of Florida Colleges of Medicine and Public Health and Health Sciences, Gainesville, FL, USA., Yu X; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.; Department of Biostatistics, University of Florida Colleges of Medicine and Public Health and Health Sciences, Gainesville, FL, USA., Tian G; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Brant JO; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA., Gauthier ML; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA., Chen J; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine; Gainesville, Florida, USA., Hernandez-Rios M; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Polcz VE; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Wiggins W; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Charles AM; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Dirain ML; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Ungaro R; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Rincon J; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Loftus T; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Xiao F; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.; Department of Biostatistics, University of Florida Colleges of Medicine and Public Health and Health Sciences, Gainesville, FL, USA., Cai G; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Moldawer LL; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Maile R; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Kladde MP; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA., Efron PA; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Mathews CE; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine; Gainesville, Florida, USA.; Department of Infectious Diseases and Immunology, University of Florida College of Veterinary Medicine; Gainesville, Florida, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 18. Date of Electronic Publication: 2025 Dec 18.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
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  Data: Prolonged Loss of Oxidative Phosphorylation and Mitochondrial Mass Characterize CD66b<superscript>+</superscript> Leukocytes from Patients with Sepsis.
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  Data: <searchLink fieldCode="AU" term="%22Rodhouse+C%22">Rodhouse C</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Barrios+EL%22">Barrios EL</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Zeumer-Spataro+L%22">Zeumer-Spataro L</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Balzano-Nogueira+L%22">Balzano-Nogueira L</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Wu+R%22">Wu R</searchLink>; 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Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine; Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Hernandez-Rios+M%22">Hernandez-Rios M</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Polcz+VE%22">Polcz VE</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Wiggins+W%22">Wiggins W</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Charles+AM%22">Charles AM</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Dirain+ML%22">Dirain ML</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Ungaro+R%22">Ungaro R</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Rincon+J%22">Rincon J</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Loftus+T%22">Loftus T</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Xiao+F%22">Xiao F</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.; Department of Biostatistics, University of Florida Colleges of Medicine and Public Health and Health Sciences, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Cai+G%22">Cai G</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Moldawer+LL%22">Moldawer LL</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Maile+R%22">Maile R</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Kladde+MP%22">Kladde MP</searchLink>; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Efron+PA%22">Efron PA</searchLink>; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Mathews+CE%22">Mathews CE</searchLink>; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine; Gainesville, Florida, USA.; Department of Infectious Diseases and Immunology, University of Florida College of Veterinary Medicine; Gainesville, Florida, USA.
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