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A window trial in metastatic pancreatic ductal adenocarcinoma reveals resistance mechanisms to targeting the KRAS-MEK pathway.

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Title: A window trial in metastatic pancreatic ductal adenocarcinoma reveals resistance mechanisms to targeting the KRAS-MEK pathway.
Authors: Tsuda M, Keith D, Daniel CJ, Pelz C, Blise KE, Ozmen TY, Ozmen F, Hawthone K, Eng JR, Li X, Wang X, Zimny H, Sivagnanam S, Betre K, Kirchberger N, Chong B, Lee J, Matter A, Smith A, Agritelley ES, Waugh T, Sannecy A, Alarcon K, Youm I, Protzek S, Egger J, English IA, Yang M, Shah VM, Link JM, Creason AL, Worth PJ, Goodyear SM, Chin K, Muschler JL, Suciu CG, Corless CL, Cao S, Soucek L, Kardosh A, Coussens LM, Brody JR, Lopez CD, Mills GB, Sears RC
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 15. Date of Electronic Publication: 2025 Dec 15.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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DbLabel: MEDLINE Ultimate
An: 41446172
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PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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