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CyTOF-based profiling of circulating tumor cells predicts aggressiveness and therapy response in SCLC liquid biopsies at a personalized level.

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Title: CyTOF-based profiling of circulating tumor cells predicts aggressiveness and therapy response in SCLC liquid biopsies at a personalized level.
Authors: Bose M; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030., Ruoff C; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030.; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Texas 77030., Ehsan S; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030.; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030., Stewart CA; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030., Duarte A Jr; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030., Bhattacharyya S; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030., Li J; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, 111 T W Alexander Dr Rall Building, Research Triangle Park, 27709, Durham, NC, United States., Benedict A; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, 111 T W Alexander Dr Rall Building, Research Triangle Park, 27709, Durham, NC, United States.; Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, United States., Welte T; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030., Victorian A; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030., Lujan FE; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030., Diao L; Department of Bioinformatics & Computational Biology, The University of Texas MD Anderson Cancer Center, Texas 77030., Wang J; Department of Bioinformatics & Computational Biology, The University of Texas MD Anderson Cancer Center, Texas 77030., Chen K; Department of Bioinformatics & Computational Biology, The University of Texas MD Anderson Cancer Center, Texas 77030., Zhang B; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030., Wang R; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030., Soto LS; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Texas 77030., Serrano AG; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Texas 77030., Cardnell R; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030., Gay CM; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030., Byers LA; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030., Karacosta LG; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 19. Date of Electronic Publication: 2025 Dec 19.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: CyTOF-based profiling of circulating tumor cells predicts aggressiveness and therapy response in SCLC liquid biopsies at a personalized level.
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  Data: <searchLink fieldCode="AU" term="%22Bose+M%22">Bose M</searchLink>; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Ruoff+C%22">Ruoff C</searchLink>; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030.; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Ehsan+S%22">Ehsan S</searchLink>; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030.; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Stewart+CA%22">Stewart CA</searchLink>; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Duarte+A+Jr%22">Duarte A Jr</searchLink>; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Bhattacharyya+S%22">Bhattacharyya S</searchLink>; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, 111 T W Alexander Dr Rall Building, Research Triangle Park, 27709, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Benedict+A%22">Benedict A</searchLink>; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, 111 T W Alexander Dr Rall Building, Research Triangle Park, 27709, Durham, NC, United States.; Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, United States.<br /><searchLink fieldCode="AU" term="%22Welte+T%22">Welte T</searchLink>; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Victorian+A%22">Victorian A</searchLink>; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Lujan+FE%22">Lujan FE</searchLink>; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Diao+L%22">Diao L</searchLink>; Department of Bioinformatics & Computational Biology, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Bioinformatics & Computational Biology, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Chen+K%22">Chen K</searchLink>; Department of Bioinformatics & Computational Biology, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Zhang+B%22">Zhang B</searchLink>; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Wang+R%22">Wang R</searchLink>; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Soto+LS%22">Soto LS</searchLink>; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Serrano+AG%22">Serrano AG</searchLink>; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Cardnell+R%22">Cardnell R</searchLink>; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Gay+CM%22">Gay CM</searchLink>; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Byers+LA%22">Byers LA</searchLink>; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Karacosta+LG%22">Karacosta LG</searchLink>; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Texas 77030.
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