Abnormal upregulation of SPP1 promotes fibrotic scar after peripheral nerve repair (FS-PNR) by driving M2 macrophage polarization.
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| Title: | Abnormal upregulation of SPP1 promotes fibrotic scar after peripheral nerve repair (FS-PNR) by driving M2 macrophage polarization. |
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| Authors: | Fan J; Department of Microsurgery, Trauma and Hand Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 51080, China., Li Z; Department of Microsurgery, Trauma and Hand Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 51080, China., Zhang N; Department of Medical Ultrasonics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangzhou 51080, China., Wang S; Department of Microsurgery, Trauma and Hand Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 51080, China., Zheng C; Department of Microsurgery, Trauma and Hand Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 51080, China; Guangdong Province Engineering Laboratory for Soft Tissue Biofabrication, Sun-Yat-sen University, Guangzhou 510080, China; Guangdong Provincial Key Laboratory for Orthopedics and Traumatology, Guangzhou 510080, China., Zhu Q; Department of Microsurgery, Trauma and Hand Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 51080, China; Guangdong Province Engineering Laboratory for Soft Tissue Biofabrication, Sun-Yat-sen University, Guangzhou 510080, China; Guangdong Provincial Key Laboratory for Orthopedics and Traumatology, Guangzhou 510080, China., Wang H; Department of Microsurgery, Trauma and Hand Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 51080, China; Guangdong Province Engineering Laboratory for Soft Tissue Biofabrication, Sun-Yat-sen University, Guangzhou 510080, China; Guangdong Provincial Key Laboratory for Orthopedics and Traumatology, Guangzhou 510080, China., Qi J; Department of Microsurgery, Trauma and Hand Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 51080, China; Guangdong Province Engineering Laboratory for Soft Tissue Biofabrication, Sun-Yat-sen University, Guangzhou 510080, China; Guangdong Provincial Key Laboratory for Orthopedics and Traumatology, Guangzhou 510080, China. Electronic address: qijian@mail.sysu.edu.cn., Yan L; Department of Microsurgery, Trauma and Hand Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 51080, China; Guangdong Province Engineering Laboratory for Soft Tissue Biofabrication, Sun-Yat-sen University, Guangzhou 510080, China; Guangdong Provincial Key Laboratory for Orthopedics and Traumatology, Guangzhou 510080, China. Electronic address: yanlw5@mail.sysu.edu.cn. |
| Source: | Experimental neurology [Exp Neurol] 2026 Apr; Vol. 398, pp. 115612. Date of Electronic Publication: 2025 Dec 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Academic Press Country of Publication: United States NLM ID: 0370712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2430 (Electronic) Linking ISSN: 00144886 NLM ISO Abbreviation: Exp Neurol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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