Topical antibiotic therapy to reduce infection after operative treatment of fractures at high risk of infection: TOBRA-a multicenter randomized controlled trial protocol.

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Title: Topical antibiotic therapy to reduce infection after operative treatment of fractures at high risk of infection: TOBRA-a multicenter randomized controlled trial protocol.
Authors: O'Toole RV; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD., Carlini AR; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD., Schrank GM; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD., O'Hara NN; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD., Chung S; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD., Gary JL; Department of Orthopaedic Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA., Obremskey W; Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN., Matuszewski PE; Department of Orthopaedic Surgery, University of Kentucky, Lexington, KY., Teague D; Department of Orthopedic Surgery and Rehabilitation, University of Oklahoma, Oklahoma City, OK., Natoli RM; Department of Orthopaedic Surgery, Methodist Hospital, Indiana University, Indianapolis, IN., Degani Y; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD., Collins SC; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD., Howe AL; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD., Thompson RE; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD., Castillo RC; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Source: OTA international : the open access journal of orthopaedic trauma [OTA Int] 2025 Dec 24; Vol. 9 (1), pp. e459. Date of Electronic Publication: 2025 Dec 24 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 101770383 Publication Model: eCollection Cited Medium: Internet ISSN: 2574-2167 (Electronic) Linking ISSN: 25742167 NLM ISO Abbreviation: OTA Int Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="JN" term="%22101770383%22">OTA international : the open access journal of orthopaedic trauma</searchLink> [OTA Int] 2025 Dec 24; Vol. 9 (1), pp. e459. <i>Date of Electronic Publication: </i>2025 Dec 24 (<i>Print Publication: </i>2026).
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