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GLP-1 receptor agonist use during immune checkpoint inhibitor therapy is associated with mortality and Immune-Related adverse events across cancer types in People with type 2 Diabetes: A Target-Trial emulation.

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Title: GLP-1 receptor agonist use during immune checkpoint inhibitor therapy is associated with mortality and Immune-Related adverse events across cancer types in People with type 2 Diabetes: A Target-Trial emulation.
Authors: Chan SH; Department of Medical Imaging and Radiology, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan. Electronic address: shchan@ms.szmc.edu.tw., Li PY; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan; School of Medicine, Chung Shan Medical University Taichung, Taiwan. Electronic address: peiyunli@csh.org.tw., Li PH; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan; School of Medicine, Chung Shan Medical University Taichung, Taiwan. Electronic address: s0617034@gm.csmu.edu.tw., Lin YJ; Department of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan. Electronic address: tch32233@tzuchi.com.tw., Wang WH; Department of Medical Imaging and Radiology, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan; Department of Orthopedic Surgery, Changhua Christian Hospital, Changhua, Taiwan; Department of Golden-Ager Industry Management, Chaoyang University of Technology, Taichung, Taiwan. Electronic address: wangweihsun@nchu.edu.tw., Huang YN; Department of Medical Imaging and Radiology, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan; School of Medicine, Chung Shan Medical University Taichung, Taiwan. Electronic address: yunanhuang@csh.org.tw., Chen JY; Division of Neonatology, Changhua Christian Children's Hospital, Changhua, Taiwan; Division of Metabolism and Endocrinology, Yunlin Christian Hospital, Changhua, Taiwan. Electronic address: 182288@cch.org.tw.
Source: Diabetes research and clinical practice [Diabetes Res Clin Pract] 2026 Jan; Vol. 231, pp. 113073. Date of Electronic Publication: 2025 Dec 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8508335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8227 (Electronic) Linking ISSN: 01688227 NLM ISO Abbreviation: Diabetes Res Clin Pract Subsets: MEDLINE
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  Data: GLP-1 receptor agonist use during immune checkpoint inhibitor therapy is associated with mortality and Immune-Related adverse events across cancer types in People with type 2 Diabetes: A Target-Trial emulation.
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  Data: <searchLink fieldCode="AU" term="%22Chan+SH%22">Chan SH</searchLink>; Department of Medical Imaging and Radiology, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan. Electronic address: shchan@ms.szmc.edu.tw.<br /><searchLink fieldCode="AU" term="%22Li+PY%22">Li PY</searchLink>; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan; School of Medicine, Chung Shan Medical University Taichung, Taiwan. Electronic address: peiyunli@csh.org.tw.<br /><searchLink fieldCode="AU" term="%22Li+PH%22">Li PH</searchLink>; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan; School of Medicine, Chung Shan Medical University Taichung, Taiwan. Electronic address: s0617034@gm.csmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Lin+YJ%22">Lin YJ</searchLink>; Department of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan. Electronic address: tch32233@tzuchi.com.tw.<br /><searchLink fieldCode="AU" term="%22Wang+WH%22">Wang WH</searchLink>; Department of Medical Imaging and Radiology, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan; Department of Orthopedic Surgery, Changhua Christian Hospital, Changhua, Taiwan; Department of Golden-Ager Industry Management, Chaoyang University of Technology, Taichung, Taiwan. Electronic address: wangweihsun@nchu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Huang+YN%22">Huang YN</searchLink>; Department of Medical Imaging and Radiology, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan; School of Medicine, Chung Shan Medical University Taichung, Taiwan. Electronic address: yunanhuang@csh.org.tw.<br /><searchLink fieldCode="AU" term="%22Chen+JY%22">Chen JY</searchLink>; Division of Neonatology, Changhua Christian Children's Hospital, Changhua, Taiwan; Division of Metabolism and Endocrinology, Yunlin Christian Hospital, Changhua, Taiwan. Electronic address: 182288@cch.org.tw.
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  Data: <searchLink fieldCode="JN" term="%228508335%22">Diabetes research and clinical practice</searchLink> [Diabetes Res Clin Pract] 2026 Jan; Vol. 231, pp. 113073. <i>Date of Electronic Publication: </i>2025 Dec 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Scientific+Publishers%22">Elsevier Scientific Publishers </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>8508335 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-8227 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201688227%22">01688227 </searchLink><i>NLM ISO Abbreviation: </i>Diabetes Res Clin Pract <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.diabres.2025.113073
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      – Code: eng
        Text: English
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      – TitleFull: GLP-1 receptor agonist use during immune checkpoint inhibitor therapy is associated with mortality and Immune-Related adverse events across cancer types in People with type 2 Diabetes: A Target-Trial emulation.
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            NameFull: Huang YN
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              Text: 2026 Jan
              Type: published
              Y: 2026
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