Large-bore mechanical thrombectomy vs standard of care for acute high-risk pulmonary embolism: Rationale and design of the PERSEVERE randomized controlled trial.
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| Title: | Large-bore mechanical thrombectomy vs standard of care for acute high-risk pulmonary embolism: Rationale and design of the PERSEVERE randomized controlled trial. |
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| Authors: | Chopard R; Department of Cardiology, University Hospital Besancon, Besancon, France; SINERGIES Laboratory, University Marie & Louis Pasteur, Besancon, France; INNO-VTE F-CRIN, Saint Etienne, France., Hobohm L; University Medical Center of Johannes Gutenberg University, Mainz, Germany., Barco S; Department of Vascular Medicine, University Hospital Zurich, Zurich, Switzerland; Center for Thrombosis and Hemostasis, University Hospital Mainz, Mainz, Germany., Bangalore S; Division of Cardiology, New York University Grossman School of Medicine, New York, NY., Giri J; Hospital of the University of Pennsylvania, Philadelphia, PA., Mahfoud F; Department of Cardiology, University Heart Center, University Hospital Basel, Basel, Switzerland; Cardiovascular Research Institute Basel (CRIB), University Heart Center, University Hospital Basel, Basel, Switzerland., Moriarty J; University of California Los Angeles, Los Angeles, CA., Rosenkranz S; Clinic III for Internal Medicine (Dept. of Cardiology), Heart Center at the University Hospital Cologne, and Cologne Cardiovascular Research Center (CCRC), Heart Center at the University Hospital Cologne and Medical Faculty, University of Cologne, Cologne, Germany., Sharp A; School of Medicine, University College Dublin and The Mater Misericordiae Hospital, Dublin, Ireland., Thiele H; University of Leipzig, Leipzig, Germany., Toma C; University of Pittsburgh Medical Center, Pittsburgh, PA., Tapson VF; Inari, Irvine, CA; Cedars-Sinai Medical Center, Los Angeles, CA., Markovitz CD; Inari, Irvine, CA., Rosenberg SP; Inari, Irvine, CA., Konstantinides S; University Medical Center of Johannes Gutenberg University, Mainz, Germany., Meneveau N; Department of Cardiology, University Hospital Besancon, Besancon, France; SINERGIES Laboratory, University Marie & Louis Pasteur, Besancon, France; INNO-VTE F-CRIN, Saint Etienne, France. Electronic address: Nicolas.meneveau@univ-fcomte.fr. |
| Source: | American heart journal [Am Heart J] 2026 Apr; Vol. 294, pp. 107331. Date of Electronic Publication: 2025 Dec 24. |
| Publication Type: | Journal Article; Clinical Trial Protocol |
| Journal Info: | Publisher: Mosby Country of Publication: United States NLM ID: 0370465 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6744 (Electronic) Linking ISSN: 00028703 NLM ISO Abbreviation: Am Heart J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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