Photocontrolled trimethoprim PROTACs targeting the eDHFR protein tag.
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| Title: | Photocontrolled trimethoprim PROTACs targeting the eDHFR protein tag. |
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| Authors: | Sharma N; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sarkar S; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Ko T; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA., Edwards KJ; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Pham JM; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Nguyen T; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Gong AZ; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Flores J; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA., Trauner D; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA. dtrauner@upenn.edu., Sellmyer MA; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. mark.sellmyer@pennmedicine.upenn.edu.; The Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. mark.sellmyer@pennmedicine.upenn.edu. |
| Source: | Nature communications [Nat Commun] 2025 Dec 27; Vol. 17 (1), pp. 822. Date of Electronic Publication: 2025 Dec 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41453904 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Photocontrolled trimethoprim PROTACs targeting the eDHFR protein tag. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Sharma+N%22">Sharma N</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Sarkar+S%22">Sarkar S</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ko+T%22">Ko T</searchLink>; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Edwards+KJ%22">Edwards KJ</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Pham+JM%22">Pham JM</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+T%22">Nguyen T</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Gong+AZ%22">Gong AZ</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Flores+J%22">Flores J</searchLink>; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Trauner+D%22">Trauner D</searchLink>; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA. dtrauner@upenn.edu.<br /><searchLink fieldCode="AU" term="%22Sellmyer+MA%22">Sellmyer MA</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. mark.sellmyer@pennmedicine.upenn.edu.; The Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. mark.sellmyer@pennmedicine.upenn.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Dec 27; Vol. 17 (1), pp. 822. <i>Date of Electronic Publication: </i>2025 Dec 27. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41453904 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41467-025-67527-5 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 822 Titles: – TitleFull: Photocontrolled trimethoprim PROTACs targeting the eDHFR protein tag. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sharma N – PersonEntity: Name: NameFull: Sarkar S – PersonEntity: Name: NameFull: Ko T – PersonEntity: Name: NameFull: Edwards KJ – PersonEntity: Name: NameFull: Pham JM – PersonEntity: Name: NameFull: Nguyen T – PersonEntity: Name: NameFull: Gong AZ – PersonEntity: Name: NameFull: Flores J – PersonEntity: Name: NameFull: Trauner D – PersonEntity: Name: NameFull: Sellmyer MA IsPartOfRelationships: – BibEntity: Dates: – D: 27 M: 12 Text: 2025 Dec 27 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2041-1723 Numbering: – Type: volume Value: 17 – Type: issue Value: 1 Titles: – TitleFull: Nature communications Type: main |
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