Photocontrolled trimethoprim PROTACs targeting the eDHFR protein tag.

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Title: Photocontrolled trimethoprim PROTACs targeting the eDHFR protein tag.
Authors: Sharma N; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sarkar S; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Ko T; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA., Edwards KJ; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Pham JM; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Nguyen T; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Gong AZ; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Flores J; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA., Trauner D; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA. dtrauner@upenn.edu., Sellmyer MA; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. mark.sellmyer@pennmedicine.upenn.edu.; The Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. mark.sellmyer@pennmedicine.upenn.edu.
Source: Nature communications [Nat Commun] 2025 Dec 27; Vol. 17 (1), pp. 822. Date of Electronic Publication: 2025 Dec 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Sharma+N%22">Sharma N</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Sarkar+S%22">Sarkar S</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ko+T%22">Ko T</searchLink>; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Edwards+KJ%22">Edwards KJ</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Pham+JM%22">Pham JM</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+T%22">Nguyen T</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Gong+AZ%22">Gong AZ</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Flores+J%22">Flores J</searchLink>; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Trauner+D%22">Trauner D</searchLink>; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA. dtrauner@upenn.edu.<br /><searchLink fieldCode="AU" term="%22Sellmyer+MA%22">Sellmyer MA</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. mark.sellmyer@pennmedicine.upenn.edu.; The Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. mark.sellmyer@pennmedicine.upenn.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Dec 27; Vol. 17 (1), pp. 822. <i>Date of Electronic Publication: </i>2025 Dec 27.
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              Text: 2025 Dec 27
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