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3D printed sex-specific medicines: Excipient-mediated modulation boosts systemic drug exposure by more than three-fold in male rats.

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Title: 3D printed sex-specific medicines: Excipient-mediated modulation boosts systemic drug exposure by more than three-fold in male rats.
Authors: Nandiraju LP; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom., Januskaite P; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom., Ruan S; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom., Qin Y; School of Pharmaceutical Sciences (Shenzen), Sun Yat-Sen University, Shenzen 518107, China., Seoane-Viaño I; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom; Department of Pharmacology, Pharmacy and Pharmaceutical Technology, Paraquasil Group (GI-2109), Faculty of Pharmacy, iMATUS and Health Research Institute of Santiago de Compostela (IDIS), University of Santiago de Compostela (USC), Santiago de Compostela 15782, Spain., Madla CM; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom; UCL Business Ltd., 90 Tottenham Ct Rd, London W1T 4TJ, UK., Chen K; School of Pharmaceutical Sciences (Shenzen), Sun Yat-Sen University, Shenzen 518107, China., Goyanes A; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom; FABRX Ltd., Henwood House, Henwood, Ashford, Kent TN24 8DH, UK; FABRX Artificial Intelligence, Calle Enrique Vidal Abascal 7 Bajo, Santiago de Compostela, CP 15702, Spain; Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, I+D Farma Group (GI-1645), Facultad de Farmacia, iMATUS and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, 15782, Spain. Electronic address: a.goyanes@fabrx.co.uk., Mai Y; School of Pharmaceutical Sciences (Shenzen), Sun Yat-Sen University, Shenzen 518107, China. Electronic address: maiy6@mail.sysu.edu.cn., Basit AW; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom; FABRX Ltd., Henwood House, Henwood, Ashford, Kent TN24 8DH, UK. Electronic address: a.basit@ucl.ac.uk.
Source: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2026 Feb 10; Vol. 390, pp. 114577. Date of Electronic Publication: 2025 Dec 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: 3D printed sex-specific medicines: Excipient-mediated modulation boosts systemic drug exposure by more than three-fold in male rats.
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  Data: <searchLink fieldCode="AU" term="%22Nandiraju+LP%22">Nandiraju LP</searchLink>; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Januskaite+P%22">Januskaite P</searchLink>; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ruan+S%22">Ruan S</searchLink>; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Qin+Y%22">Qin Y</searchLink>; School of Pharmaceutical Sciences (Shenzen), Sun Yat-Sen University, Shenzen 518107, China.<br /><searchLink fieldCode="AU" term="%22Seoane-Viaño+I%22">Seoane-Viaño I</searchLink>; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom; Department of Pharmacology, Pharmacy and Pharmaceutical Technology, Paraquasil Group (GI-2109), Faculty of Pharmacy, iMATUS and Health Research Institute of Santiago de Compostela (IDIS), University of Santiago de Compostela (USC), Santiago de Compostela 15782, Spain.<br /><searchLink fieldCode="AU" term="%22Madla+CM%22">Madla CM</searchLink>; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom; UCL Business Ltd., 90 Tottenham Ct Rd, London W1T 4TJ, UK.<br /><searchLink fieldCode="AU" term="%22Chen+K%22">Chen K</searchLink>; School of Pharmaceutical Sciences (Shenzen), Sun Yat-Sen University, Shenzen 518107, China.<br /><searchLink fieldCode="AU" term="%22Goyanes+A%22">Goyanes A</searchLink>; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom; FABRX Ltd., Henwood House, Henwood, Ashford, Kent TN24 8DH, UK; FABRX Artificial Intelligence, Calle Enrique Vidal Abascal 7 Bajo, Santiago de Compostela, CP 15702, Spain; Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, I+D Farma Group (GI-1645), Facultad de Farmacia, iMATUS and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, 15782, Spain. Electronic address: a.goyanes@fabrx.co.uk.<br /><searchLink fieldCode="AU" term="%22Mai+Y%22">Mai Y</searchLink>; School of Pharmaceutical Sciences (Shenzen), Sun Yat-Sen University, Shenzen 518107, China. Electronic address: maiy6@mail.sysu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Basit+AW%22">Basit AW</searchLink>; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom; FABRX Ltd., Henwood House, Henwood, Ashford, Kent TN24 8DH, UK. Electronic address: a.basit@ucl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%228607908%22">Journal of controlled release : official journal of the Controlled Release Society</searchLink> [J Control Release] 2026 Feb 10; Vol. 390, pp. 114577. <i>Date of Electronic Publication: </i>2025 Dec 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Publishers%22">Elsevier Science Publishers </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8607908 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4995 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201683659%22">01683659 </searchLink><i>NLM ISO Abbreviation: </i>J Control Release <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jconrel.2025.114577
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        Text: English
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      – TitleFull: 3D printed sex-specific medicines: Excipient-mediated modulation boosts systemic drug exposure by more than three-fold in male rats.
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              Text: 2026 Feb 10
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