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Immunohistochemical evaluation of EGFR protein expression and microvascular density reveals an angiogenic signature in Tunisian patients with metastatic colorectal cancer.

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Title: Immunohistochemical evaluation of EGFR protein expression and microvascular density reveals an angiogenic signature in Tunisian patients with metastatic colorectal cancer.
Authors: Gabteni AJ; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia. amira.jaballah@pasteur.utm.tn.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia. amira.jaballah@pasteur.utm.tn., Ben Ayed I; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Yaiche H; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Ben Jemii N; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Wider D; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Ardhaoui M; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Molecular Epidemiology and Experimental Pathology (LR16IPT04), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Fehri E; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Molecular Epidemiology and Experimental Pathology (LR16IPT04), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Maaloul A; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia., Habbechi E; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia., Ennaifer E; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Molecular Epidemiology and Experimental Pathology (LR16IPT04), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Tounsi H; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Source: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2026 Jun; Vol. 28 (6), pp. 2246-2258. Date of Electronic Publication: 2025 Dec 28.
Publication Type: Journal Article
Journal Info: Publisher: Country of Publication: Italy NLM ID: 101247119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-3055 (Electronic) Linking ISSN: 1699048X NLM ISO Abbreviation: Clin Transl Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Immunohistochemical evaluation of EGFR protein expression and microvascular density reveals an angiogenic signature in Tunisian patients with metastatic colorectal cancer.
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  Data: <searchLink fieldCode="AU" term="%22Gabteni+AJ%22">Gabteni AJ</searchLink>; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia. amira.jaballah@pasteur.utm.tn.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia. amira.jaballah@pasteur.utm.tn.<br /><searchLink fieldCode="AU" term="%22Ben+Ayed+I%22">Ben Ayed I</searchLink>; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Yaiche+H%22">Yaiche H</searchLink>; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Ben+Jemii+N%22">Ben Jemii N</searchLink>; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Wider+D%22">Wider D</searchLink>; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Ardhaoui+M%22">Ardhaoui M</searchLink>; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Molecular Epidemiology and Experimental Pathology (LR16IPT04), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Fehri+E%22">Fehri E</searchLink>; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Molecular Epidemiology and Experimental Pathology (LR16IPT04), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Maaloul+A%22">Maaloul A</searchLink>; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Habbechi+E%22">Habbechi E</searchLink>; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Ennaifer+E%22">Ennaifer E</searchLink>; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Molecular Epidemiology and Experimental Pathology (LR16IPT04), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Tounsi+H%22">Tounsi H</searchLink>; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
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      – TitleFull: Immunohistochemical evaluation of EGFR protein expression and microvascular density reveals an angiogenic signature in Tunisian patients with metastatic colorectal cancer.
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              Text: 2026 Jun
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