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Immunohistochemical evaluation of EGFR protein expression and microvascular density reveals an angiogenic signature in Tunisian patients with metastatic colorectal cancer.

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Title: Immunohistochemical evaluation of EGFR protein expression and microvascular density reveals an angiogenic signature in Tunisian patients with metastatic colorectal cancer.
Authors: Gabteni AJ; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia. amira.jaballah@pasteur.utm.tn.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia. amira.jaballah@pasteur.utm.tn., Ben Ayed I; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Yaiche H; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Ben Jemii N; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Wider D; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Ardhaoui M; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Molecular Epidemiology and Experimental Pathology (LR16IPT04), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Fehri E; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Molecular Epidemiology and Experimental Pathology (LR16IPT04), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Maaloul A; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia., Habbechi E; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia., Ennaifer E; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Molecular Epidemiology and Experimental Pathology (LR16IPT04), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Tounsi H; Department of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia.; Laboratory of Biomedical Genomics and Oncogenetics (LR20IPT05), Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Source: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2026 Jun; Vol. 28 (6), pp. 2246-2258. Date of Electronic Publication: 2025 Dec 28.
Publication Type: Journal Article
Journal Info: Publisher: Country of Publication: Italy NLM ID: 101247119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-3055 (Electronic) Linking ISSN: 1699048X NLM ISO Abbreviation: Clin Transl Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1699-3055
DOI:10.1007/s12094-025-04176-6