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Antibodies against polysaccharide type 3 and pneumococcal proteins demonstrate synergistic protective effect in a highly virulent type 3 invasive disease model in mice.

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Title: Antibodies against polysaccharide type 3 and pneumococcal proteins demonstrate synergistic protective effect in a highly virulent type 3 invasive disease model in mice.
Authors: Stevenson TC; GSK, Cambridge, MA, United States., Burke H; GSK, Cambridge, MA, United States., Roggensack SE; GSK, Cambridge, MA, United States., Pratt A; GSK, Cambridge, MA, United States., Hossain A; GSK, Cambridge, MA, United States., Ghosh P; Affinivax, Inc., Cambridge, MA, United States., Besin G; Affinivax, Inc., Cambridge, MA, United States., Lu Y; Division of Infectious Diseases, Department of Medicine, Boston Children's Hospital, Boston, MA, United States., Zhang F; Division of Infectious Diseases, Department of Medicine, Boston Children's Hospital, Boston, MA, United States., Malley R; Division of Infectious Diseases, Department of Medicine, Boston Children's Hospital, Boston, MA, United States., Sebastian S; GSK, Cambridge, MA, United States.
Source: Frontiers in immunology [Front Immunol] 2025 Dec 12; Vol. 16, pp. 1707686. Date of Electronic Publication: 2025 Dec 12 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Antibodies against polysaccharide type 3 and pneumococcal proteins demonstrate synergistic protective effect in a highly virulent type 3 invasive disease model in mice.
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  Data: <searchLink fieldCode="AU" term="%22Stevenson+TC%22">Stevenson TC</searchLink>; GSK, Cambridge, MA, United States.<br /><searchLink fieldCode="AU" term="%22Burke+H%22">Burke H</searchLink>; GSK, Cambridge, MA, United States.<br /><searchLink fieldCode="AU" term="%22Roggensack+SE%22">Roggensack SE</searchLink>; GSK, Cambridge, MA, United States.<br /><searchLink fieldCode="AU" term="%22Pratt+A%22">Pratt A</searchLink>; GSK, Cambridge, MA, United States.<br /><searchLink fieldCode="AU" term="%22Hossain+A%22">Hossain A</searchLink>; GSK, Cambridge, MA, United States.<br /><searchLink fieldCode="AU" term="%22Ghosh+P%22">Ghosh P</searchLink>; Affinivax, Inc., Cambridge, MA, United States.<br /><searchLink fieldCode="AU" term="%22Besin+G%22">Besin G</searchLink>; Affinivax, Inc., Cambridge, MA, United States.<br /><searchLink fieldCode="AU" term="%22Lu+Y%22">Lu Y</searchLink>; Division of Infectious Diseases, Department of Medicine, Boston Children's Hospital, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Zhang+F%22">Zhang F</searchLink>; Division of Infectious Diseases, Department of Medicine, Boston Children's Hospital, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Malley+R%22">Malley R</searchLink>; Division of Infectious Diseases, Department of Medicine, Boston Children's Hospital, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Sebastian+S%22">Sebastian S</searchLink>; GSK, Cambridge, MA, United States.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2025 Dec 12; Vol. 16, pp. 1707686. <i>Date of Electronic Publication: </i>2025 Dec 12 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.3389/fimmu.2025.1707686
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      – Code: eng
        Text: English
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        StartPage: 1707686
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      – TitleFull: Antibodies against polysaccharide type 3 and pneumococcal proteins demonstrate synergistic protective effect in a highly virulent type 3 invasive disease model in mice.
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            – D: 12
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              Text: 2025 Dec 12
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              Y: 2025
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