Lobectomy-first versus lymphadenectomy-first on long-term survival for operable non-small cell lung cancer: protocol of LOFTY trial.

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Title: Lobectomy-first versus lymphadenectomy-first on long-term survival for operable non-small cell lung cancer: protocol of LOFTY trial.
Authors: Fan HR; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China., Yang MZ; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China., Yan XL; Department of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China., Chen XB; Department of Thoracic Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, China., Gou YJ; Department of Thoracic Surgery, Gansu Provincial Hospital, Lanzhou, China., You J; Department of Lung Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China., Lin JB; Department of Thoracic Surgery, Fujian Medical University Union Hospital, Fuzhou, China., Zhou HN; Department of Thoracic Surgery, Suining Central Hospital, Suining, China., Zhang H; Department of Thoracic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China., Chen WS; Department of Thoracic Surgery, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China., Zhang N; Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Tang H; Department of Thoracic Surgery, Second Affiliated Hospital of Naval Medical University, Shanghai, China., Lin YB; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China., Leng XF; Division of Thoracic Surgery, Sichuan Cancer Hospital and Institute, Chengdu, China., Qian XZ; Department of Thoracic Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Yi J; Department of Cardiothoracic Surgery, The General Hospital of Eastern Theater Command, Nanjing, China., Su XD; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China., Cai SW; Department of Thoracic Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China., Gu WQ; Department of Thoracic Surgery, The First People's Hospital of Foshan, Foshan, China., Peng ZM; Department of Thoracic Surgery, Provincial Hospital, Shandong First Medical University, Jinan, China., Du W; Department of Thoracic Surgery, The People's Hospital of Dongguan, Dongguan, China., Yang H; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China., Mei JD; Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China., Sun DQ; Department of Thoracic Surgery, Tianjin Chest Hospital, Tianjin, China., Liao YD; Department of Thoracic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Liao HY; Department of Thoracic Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China., Qiu B; Department of Thoracic Surgery, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing, China., Ma GW; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China., Jiao WJ; Department of Thoracic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China., Wang W; Department of Thoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Wang Y; Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China., Zhao ZR; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China., Liu QW; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China., Sun TY; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China., Li M; Department of Thoracic Surgery, Nanjing Medical University Affiliated Cancer Hospital, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing, China., Yang HX; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China. yanghx@sysucc.org.cn.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China. yanghx@sysucc.org.cn.
Source: Trials [Trials] 2025 Dec 29; Vol. 26 (1), pp. 581. Date of Electronic Publication: 2025 Dec 29.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Lobectomy-first versus lymphadenectomy-first on long-term survival for operable non-small cell lung cancer: protocol of LOFTY trial.
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  Data: <searchLink fieldCode="AU" term="%22Fan+HR%22">Fan HR</searchLink>; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yang+MZ%22">Yang MZ</searchLink>; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yan+XL%22">Yan XL</searchLink>; Department of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Chen+XB%22">Chen XB</searchLink>; Department of Thoracic Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Gou+YJ%22">Gou YJ</searchLink>; Department of Thoracic Surgery, Gansu Provincial Hospital, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22You+J%22">You J</searchLink>; Department of Lung Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Lin+JB%22">Lin JB</searchLink>; Department of Thoracic Surgery, Fujian Medical University Union Hospital, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhou+HN%22">Zhou HN</searchLink>; Department of Thoracic Surgery, Suining Central Hospital, Suining, China.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Department of Thoracic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+WS%22">Chen WS</searchLink>; Department of Thoracic Surgery, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+N%22">Zhang N</searchLink>; Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Tang+H%22">Tang H</searchLink>; Department of Thoracic Surgery, Second Affiliated Hospital of Naval Medical University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Lin+YB%22">Lin YB</searchLink>; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Leng+XF%22">Leng XF</searchLink>; Division of Thoracic Surgery, Sichuan Cancer Hospital and Institute, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Qian+XZ%22">Qian XZ</searchLink>; Department of Thoracic Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yi+J%22">Yi J</searchLink>; Department of Cardiothoracic Surgery, The General Hospital of Eastern Theater Command, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Su+XD%22">Su XD</searchLink>; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Cai+SW%22">Cai SW</searchLink>; Department of Thoracic Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Gu+WQ%22">Gu WQ</searchLink>; Department of Thoracic Surgery, The First People's Hospital of Foshan, Foshan, China.<br /><searchLink fieldCode="AU" term="%22Peng+ZM%22">Peng ZM</searchLink>; Department of Thoracic Surgery, Provincial Hospital, Shandong First Medical University, Jinan, China.<br /><searchLink fieldCode="AU" term="%22Du+W%22">Du W</searchLink>; Department of Thoracic Surgery, The People's Hospital of Dongguan, Dongguan, China.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Mei+JD%22">Mei JD</searchLink>; Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Sun+DQ%22">Sun DQ</searchLink>; Department of Thoracic Surgery, Tianjin Chest Hospital, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Liao+YD%22">Liao YD</searchLink>; Department of Thoracic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Liao+HY%22">Liao HY</searchLink>; Department of Thoracic Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Qiu+B%22">Qiu B</searchLink>; Department of Thoracic Surgery, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Ma+GW%22">Ma GW</searchLink>; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Jiao+WJ%22">Jiao WJ</searchLink>; Department of Thoracic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; Department of Thoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Zhao+ZR%22">Zhao ZR</searchLink>; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+QW%22">Liu QW</searchLink>; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Sun+TY%22">Sun TY</searchLink>; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Department of Thoracic Surgery, Nanjing Medical University Affiliated Cancer Hospital, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Yang+HX%22">Yang HX</searchLink>; Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, 510060, China. yanghx@sysucc.org.cn.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China. yanghx@sysucc.org.cn.
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  Data: <searchLink fieldCode="JN" term="%22101263253%22">Trials</searchLink> [Trials] 2025 Dec 29; Vol. 26 (1), pp. 581. <i>Date of Electronic Publication: </i>2025 Dec 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101263253 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1745-6215 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217456215%22">17456215 </searchLink><i>NLM ISO Abbreviation: </i>Trials <i>Subsets: </i>MEDLINE
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