Assessment of Collagen and Fibroblast Properties via Label-Free Higher Harmonic Generation Microscopy in Three-Dimensional Models of Osteogenesis Imperfecta and Ehlers-Danlos Syndrome.

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Title: Assessment of Collagen and Fibroblast Properties via Label-Free Higher Harmonic Generation Microscopy in Three-Dimensional Models of Osteogenesis Imperfecta and Ehlers-Danlos Syndrome.
Authors: Ma Y; Department of Physics, LaserLab Amsterdam, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands., Bo Q; Institute of Modern Optics, Nankai University, Tianjin 300350, China., Zhang Z; Institute of Modern Optics, Nankai University, Tianjin 300350, China., van Haasterecht L; Department of Physics, LaserLab Amsterdam, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands., Kloen P; Department of Orthopedic Surgery and Sports Medicine, Amsterdam University Medical Center, Location Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.; Amsterdam Movement Sciences, 1081 BT Amsterdam, The Netherlands., Rustemeyer T; The Netherlands Department of Dermato-Allergology and Occupational Health, Amsterdam University Medical Center, Location AMC, University of Amsterdam, 1000 GG Amsterdam, The Netherlands., Ventura L; Amsterdam Movement Sciences, 1081 BT Amsterdam, The Netherlands.; Amsterdam Reproduction & Development, 1105 AZ Amsterdam, The Netherlands.; Rare Bone Disease Center Amsterdam, 1081 HV Amsterdam, The Netherlands.; Department of Human Genetics, Amsterdam University Medical Center, Location Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands., Zhytnik L; Amsterdam Movement Sciences, 1081 BT Amsterdam, The Netherlands.; Amsterdam Reproduction & Development, 1105 AZ Amsterdam, The Netherlands.; Rare Bone Disease Center Amsterdam, 1081 HV Amsterdam, The Netherlands.; Department of Human Genetics, Amsterdam University Medical Center, Location Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands., Eekhoff EMW; Rare Bone Disease Center Amsterdam, 1081 HV Amsterdam, The Netherlands.; Department of Endocrinology & Metabolism, Amsterdam University Medical Center, Location Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands., Micha D; Rare Bone Disease Center Amsterdam, 1081 HV Amsterdam, The Netherlands.; Department of Human Genetics, Amsterdam University Medical Center, Location Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands., Groot ML; Department of Physics, LaserLab Amsterdam, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.
Source: International journal of molecular sciences [Int J Mol Sci] 2025 Dec 08; Vol. 26 (24). Date of Electronic Publication: 2025 Dec 08.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1422-0067
DOI:10.3390/ijms262411848