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A double-blind, placebo-controlled, multi-crossover trial of treatment with a chemokine antagonist for knee osteoarthritis pain.

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Title: A double-blind, placebo-controlled, multi-crossover trial of treatment with a chemokine antagonist for knee osteoarthritis pain.
Authors: Edwards RR; Mass General Brigham, Harvard Medical School, Boston, MA, United States., Tarpey T; NYU Langone, New York, NY, United States., Ashburn M; University of Pennsylvania, Philadelphia, PA, United States., Baer C; NYU Langone, New York, NY, United States., Campbell A; Mass General Brigham, Harvard Medical School, Boston, MA, United States., Dworkin RH; University of Rochester, Rochester, NY, United States., Gaspard G; NYU Langone, New York, NY, United States., Flynn M; Mass General Brigham, Harvard Medical School, Boston, MA, United States., Hade E; NYU Langone, New York, NY, United States., Jain N; University of Michigan, Ann Arbor, MI, United States., Judge H; Mass General Brigham, Harvard Medical School, Boston, MA, United States., Kamp C; University of Rochester, Rochester, NY, United States., Li Y; NYU Langone, New York, NY, United States., Meropol S; NYU Langone, New York, NY, United States., Petkova E; NYU Langone, New York, NY, United States., Philip A; University of Rochester, Rochester, NY, United States., Przkora R; University of Florida, Gainesville, FL, United States., Rathmell JP; Mass General Brigham, Harvard Medical School, Boston, MA, United States., Robinson-Papp J; Icahn School of Medicine at Mount Sinai, New York, NY, United States., Samuels J; NYU Langone, New York, NY, United States., Sehgal N; University of Wisconsin, Madison, WI, United States., Sienty J; NYU Langone, New York, NY, United States., Stacey B; University of Washington, Seattle, WA, United States., Wallace M; University of California at San Diego, San Diego, CA, United States., Wasan AD; University of Pittsburgh, Pittsburgh, PA, United States., Wise B; University of California Davis, Sacramento, CA, United States., Yu C; NYU Langone, New York, NY, United States., Fava M; Mass General Brigham, Harvard Medical School, Boston, MA, United States., Troxel AB; NYU Langone, New York, NY, United States.
Source: Pain [Pain] 2026 May 01; Vol. 167 (5), pp. 1137-1145. Date of Electronic Publication: 2026 Jan 06.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7508686 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6623 (Electronic) Linking ISSN: 03043959 NLM ISO Abbreviation: Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A double-blind, placebo-controlled, multi-crossover trial of treatment with a chemokine antagonist for knee osteoarthritis pain.
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  Data: <searchLink fieldCode="AU" term="%22Edwards+RR%22">Edwards RR</searchLink>; Mass General Brigham, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Tarpey+T%22">Tarpey T</searchLink>; NYU Langone, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Ashburn+M%22">Ashburn M</searchLink>; University of Pennsylvania, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Baer+C%22">Baer C</searchLink>; NYU Langone, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Campbell+A%22">Campbell A</searchLink>; Mass General Brigham, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Dworkin+RH%22">Dworkin RH</searchLink>; University of Rochester, Rochester, NY, United States.<br /><searchLink fieldCode="AU" term="%22Gaspard+G%22">Gaspard G</searchLink>; NYU Langone, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Flynn+M%22">Flynn M</searchLink>; Mass General Brigham, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Hade+E%22">Hade E</searchLink>; NYU Langone, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Jain+N%22">Jain N</searchLink>; University of Michigan, Ann Arbor, MI, United States.<br /><searchLink fieldCode="AU" term="%22Judge+H%22">Judge H</searchLink>; Mass General Brigham, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Kamp+C%22">Kamp C</searchLink>; University of Rochester, Rochester, NY, United States.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; NYU Langone, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Meropol+S%22">Meropol S</searchLink>; NYU Langone, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Petkova+E%22">Petkova E</searchLink>; NYU Langone, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Philip+A%22">Philip A</searchLink>; University of Rochester, Rochester, NY, United States.<br /><searchLink fieldCode="AU" term="%22Przkora+R%22">Przkora R</searchLink>; University of Florida, Gainesville, FL, United States.<br /><searchLink fieldCode="AU" term="%22Rathmell+JP%22">Rathmell JP</searchLink>; Mass General Brigham, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Robinson-Papp+J%22">Robinson-Papp J</searchLink>; Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Samuels+J%22">Samuels J</searchLink>; NYU Langone, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Sehgal+N%22">Sehgal N</searchLink>; University of Wisconsin, Madison, WI, United States.<br /><searchLink fieldCode="AU" term="%22Sienty+J%22">Sienty J</searchLink>; NYU Langone, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Stacey+B%22">Stacey B</searchLink>; University of Washington, Seattle, WA, United States.<br /><searchLink fieldCode="AU" term="%22Wallace+M%22">Wallace M</searchLink>; University of California at San Diego, San Diego, CA, United States.<br /><searchLink fieldCode="AU" term="%22Wasan+AD%22">Wasan AD</searchLink>; University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Wise+B%22">Wise B</searchLink>; University of California Davis, Sacramento, CA, United States.<br /><searchLink fieldCode="AU" term="%22Yu+C%22">Yu C</searchLink>; NYU Langone, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Fava+M%22">Fava M</searchLink>; Mass General Brigham, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Troxel+AB%22">Troxel AB</searchLink>; NYU Langone, New York, NY, United States.
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  Data: <searchLink fieldCode="JN" term="%227508686%22">Pain</searchLink> [Pain] 2026 May 01; Vol. 167 (5), pp. 1137-1145. <i>Date of Electronic Publication: </i>2026 Jan 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7508686 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-6623 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203043959%22">03043959 </searchLink><i>NLM ISO Abbreviation: </i>Pain <i>Subsets: </i>MEDLINE
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        Value: 10.1097/j.pain.0000000000003904
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