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Plasma Cell-free DNA Methylomes for Hepatocellular Carcinoma Detection and Monitoring After Liver Resection or Transplantation.

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Title: Plasma Cell-free DNA Methylomes for Hepatocellular Carcinoma Detection and Monitoring After Liver Resection or Transplantation.
Authors: Chen K; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada., Li Z; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada., Kirsh BO; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Canada., Luo P; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada., Pedersen S; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada., Bucur RC; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada., Rukavina NA; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada., Bruce JP; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada., Danesh A; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada., Riverin M; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada., Fischer SE; Laboratory Medicine Program, University Health Network, Toronto, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Canada., Bhat M; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of Gastroenterology, University Health Network, Toronto, Canada.; Department of Medicine, University of Toronto, Canada., Selzner N; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of Gastroenterology, University Health Network, Toronto, Canada.; Department of Medicine, University of Toronto, Canada., MacParland SA; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Canada., Moulton CA; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada., Gallinger S; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada., McGilvray ID; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada., Cattral MS; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada., Selzner M; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada., Reichman TW; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada., Shwaartz C; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada., Sayed BA; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada., Cleary SP; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada., Sapisochin G; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada., Ghanekar A; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada., Pugh TJ; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Canada.; Ontario Institute for Cancer Research, Toronto, Canada.
Source: Annals of surgery [Ann Surg] 2025 Dec 31. Date of Electronic Publication: 2025 Dec 31.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0372354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1140 (Electronic) Linking ISSN: 00034932 NLM ISO Abbreviation: Ann Surg Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Chen+K%22">Chen K</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Kirsh+BO%22">Kirsh BO</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Luo+P%22">Luo P</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Pedersen+S%22">Pedersen S</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Bucur+RC%22">Bucur RC</searchLink>; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Rukavina+NA%22">Rukavina NA</searchLink>; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Bruce+JP%22">Bruce JP</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Danesh+A%22">Danesh A</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Riverin+M%22">Riverin M</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Fischer+SE%22">Fischer SE</searchLink>; Laboratory Medicine Program, University Health Network, Toronto, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Bhat+M%22">Bhat M</searchLink>; 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Department of Surgery, University of Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Selzner+M%22">Selzner M</searchLink>; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Reichman+TW%22">Reichman TW</searchLink>; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Shwaartz+C%22">Shwaartz C</searchLink>; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Sayed+BA%22">Sayed BA</searchLink>; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Cleary+SP%22">Cleary SP</searchLink>; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Sapisochin+G%22">Sapisochin G</searchLink>; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Ghanekar+A%22">Ghanekar A</searchLink>; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, Canada.; Division of General Surgery, University Health Network, Toronto, Canada.; Department of Surgery, University of Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Pugh+TJ%22">Pugh TJ</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Canada.; Ontario Institute for Cancer Research, Toronto, Canada.
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