Bighorn sheep T2T genome assembly reveals differences in immune genes: a potential cause of high morbidity due to respiratory pathogens.

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Title: Bighorn sheep T2T genome assembly reveals differences in immune genes: a potential cause of high morbidity due to respiratory pathogens.
Authors: Olagunju TA; Department of Animal, Veterinary and Food Sciences, University of Idaho, Moscow, ID, USA., Pospelova M; Computer Science and Engineering Department. Pennsylvania State University, State College, University Park, PA, USA., Schwartz JC; The Pirbright Institute, Ash Road, Woking GU24 0NF, UK., Mousel MR; U.S. Department of Agriculture, Agricultural Research Service, Animal Disease Research Unit, Pullman, WA, USA.; Washington State University, Center for Global Health, Pullman, WA, USA., Piel LMW; U.S. Department of Agriculture, Agricultural Research Service, Animal Disease Research Unit, Pullman, WA, USA., Grossman PC; U.S. Department of Agriculture, Agricultural Research Service, Animal Disease Research Unit, Pullman, WA, USA., Huyvaert KP; Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, USA., Kuhn KL; U.S. Department of Agriculture Meat Animal Research Center, Clay Center, NE, USA., Raihan T; CVRC Bioinformatics Core, Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA., Stegemiller MR; Department of Animal, Veterinary and Food Sciences, University of Idaho, Moscow, ID, USA., Khilji SF; Department of Animal, Veterinary and Food Sciences, University of Idaho, Moscow, ID, USA., Murdoch GK; Department of Animal, Veterinary and Food Sciences, University of Idaho, Moscow, ID, USA.; Animal Sciences, CAHNRS, Washington State University, Pullman, WA, USA., Tibary A; Department of Veterinary Clinical Science, College of Veterinary Medicine, Washington State University, Pullman, WA, USA., Waits LP; Department of Fish and Wildlife Sciences, University of Idaho, Moscow, ID, USA., Rhie A; Genome Informatics Section, Center for Genomics and Data Science Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Koren S; Genome Informatics Section, Center for Genomics and Data Science Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Phillipy AM; Genome Informatics Section, Center for Genomics and Data Science Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., McKay SD; Division of Animal Sciences, University of Missouri, Columbia, MO, USA., Clarke SM; Animal Genomics, AgResearch, New Zealand Institute for Bioeconomy Science, Dunedin, NZ., Clark EL; European Bioinformatics Institute, Cambridge, England, GB., Brauning R; Bioinformatics and Modelling, AgResearch, New Zealand Institute for Bioeconomy Science, Christchurch, NZ., Cockett NE; Animal, Dairy, and Veterinary Sciences Department, Utah State University, Logan, UT, USA., Hammond JA; The Pirbright Institute, Ash Road, Woking GU24 0NF, UK., Highland M; Wisconsin Veterinary Diagnostic Laboratory, Madison, WI, USA.; Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA., Safonova Y; Computer Science and Engineering Department. Pennsylvania State University, State College, University Park, PA, USA.; Huck Institutes of Life Sciences, Pennsylvania State University, State College, University Park, PA, USA., Smith TPL; U.S. Department of Agriculture Meat Animal Research Center, Clay Center, NE, USA., Rosen BD; Animal Genomics and Improvement Laboratory, USDA Agricultural Research Service, Beltsville, MD, USA., Murdoch BM; Department of Animal, Veterinary and Food Sciences, University of Idaho, Moscow, ID, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Oct 02. Date of Electronic Publication: 2025 Oct 02.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Bighorn sheep T2T genome assembly reveals differences in immune genes: a potential cause of high morbidity due to respiratory pathogens.
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  Data: <searchLink fieldCode="AU" term="%22Olagunju+TA%22">Olagunju TA</searchLink>; Department of Animal, Veterinary and Food Sciences, University of Idaho, Moscow, ID, USA.<br /><searchLink fieldCode="AU" term="%22Pospelova+M%22">Pospelova M</searchLink>; Computer Science and Engineering Department. Pennsylvania State University, State College, University Park, PA, USA.<br /><searchLink fieldCode="AU" term="%22Schwartz+JC%22">Schwartz JC</searchLink>; The Pirbright Institute, Ash Road, Woking GU24 0NF, UK.<br /><searchLink fieldCode="AU" term="%22Mousel+MR%22">Mousel MR</searchLink>; U.S. Department of Agriculture, Agricultural Research Service, Animal Disease Research Unit, Pullman, WA, USA.; Washington State University, Center for Global Health, Pullman, WA, USA.<br /><searchLink fieldCode="AU" term="%22Piel+LMW%22">Piel LMW</searchLink>; U.S. Department of Agriculture, Agricultural Research Service, Animal Disease Research Unit, Pullman, WA, USA.<br /><searchLink fieldCode="AU" term="%22Grossman+PC%22">Grossman PC</searchLink>; U.S. Department of Agriculture, Agricultural Research Service, Animal Disease Research Unit, Pullman, WA, USA.<br /><searchLink fieldCode="AU" term="%22Huyvaert+KP%22">Huyvaert KP</searchLink>; Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, USA.<br /><searchLink fieldCode="AU" term="%22Kuhn+KL%22">Kuhn KL</searchLink>; U.S. Department of Agriculture Meat Animal Research Center, Clay Center, NE, USA.<br /><searchLink fieldCode="AU" term="%22Raihan+T%22">Raihan T</searchLink>; CVRC Bioinformatics Core, Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Stegemiller+MR%22">Stegemiller MR</searchLink>; Department of Animal, Veterinary and Food Sciences, University of Idaho, Moscow, ID, USA.<br /><searchLink fieldCode="AU" term="%22Khilji+SF%22">Khilji SF</searchLink>; Department of Animal, Veterinary and Food Sciences, University of Idaho, Moscow, ID, USA.<br /><searchLink fieldCode="AU" term="%22Murdoch+GK%22">Murdoch GK</searchLink>; Department of Animal, Veterinary and Food Sciences, University of Idaho, Moscow, ID, USA.; Animal Sciences, CAHNRS, Washington State University, Pullman, WA, USA.<br /><searchLink fieldCode="AU" term="%22Tibary+A%22">Tibary A</searchLink>; Department of Veterinary Clinical Science, College of Veterinary Medicine, Washington State University, Pullman, WA, USA.<br /><searchLink fieldCode="AU" term="%22Waits+LP%22">Waits LP</searchLink>; Department of Fish and Wildlife Sciences, University of Idaho, Moscow, ID, USA.<br /><searchLink fieldCode="AU" term="%22Rhie+A%22">Rhie A</searchLink>; Genome Informatics Section, Center for Genomics and Data Science Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Koren+S%22">Koren S</searchLink>; Genome Informatics Section, Center for Genomics and Data Science Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Phillipy+AM%22">Phillipy AM</searchLink>; Genome Informatics Section, Center for Genomics and Data Science Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22McKay+SD%22">McKay SD</searchLink>; Division of Animal Sciences, University of Missouri, Columbia, MO, USA.<br /><searchLink fieldCode="AU" term="%22Clarke+SM%22">Clarke SM</searchLink>; Animal Genomics, AgResearch, New Zealand Institute for Bioeconomy Science, Dunedin, NZ.<br /><searchLink fieldCode="AU" term="%22Clark+EL%22">Clark EL</searchLink>; European Bioinformatics Institute, Cambridge, England, GB.<br /><searchLink fieldCode="AU" term="%22Brauning+R%22">Brauning R</searchLink>; Bioinformatics and Modelling, AgResearch, New Zealand Institute for Bioeconomy Science, Christchurch, NZ.<br /><searchLink fieldCode="AU" term="%22Cockett+NE%22">Cockett NE</searchLink>; Animal, Dairy, and Veterinary Sciences Department, Utah State University, Logan, UT, USA.<br /><searchLink fieldCode="AU" term="%22Hammond+JA%22">Hammond JA</searchLink>; The Pirbright Institute, Ash Road, Woking GU24 0NF, UK.<br /><searchLink fieldCode="AU" term="%22Highland+M%22">Highland M</searchLink>; Wisconsin Veterinary Diagnostic Laboratory, Madison, WI, USA.; Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Safonova+Y%22">Safonova Y</searchLink>; Computer Science and Engineering Department. Pennsylvania State University, State College, University Park, PA, USA.; Huck Institutes of Life Sciences, Pennsylvania State University, State College, University Park, PA, USA.<br /><searchLink fieldCode="AU" term="%22Smith+TPL%22">Smith TPL</searchLink>; U.S. Department of Agriculture Meat Animal Research Center, Clay Center, NE, USA.<br /><searchLink fieldCode="AU" term="%22Rosen+BD%22">Rosen BD</searchLink>; Animal Genomics and Improvement Laboratory, USDA Agricultural Research Service, Beltsville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Murdoch+BM%22">Murdoch BM</searchLink>; Department of Animal, Veterinary and Food Sciences, University of Idaho, Moscow, ID, USA.
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