A novel hierarchical framework elucidating regional differences in α-synuclein and tau co-pathology in military veterans with parkinsonism.
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| Title: | A novel hierarchical framework elucidating regional differences in α-synuclein and tau co-pathology in military veterans with parkinsonism. |
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| Authors: | Flores Almazan VG; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Laborc KF; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States., De Sanctis C; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Thorn EL; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Goldstein A; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Cervera A; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Quintana Mora DF; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Neurology, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Mendez Y; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Neurology, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States., McGoldrick AC; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Neurology, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Chiu LY; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Hossain QI; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States., McQuillan S; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Lind-Watson K; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Walker JM; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, TX, United States., Walker RH; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Neurology, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Nirenberg MJ; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Neurology, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Crary JF; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States. |
| Source: | Journal of neuropathology and experimental neurology [J Neuropathol Exp Neurol] 2026 Jun 01; Vol. 85 (6), pp. 525-536. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 2985192R Publication Model: Print Cited Medium: Internet ISSN: 1554-6578 (Electronic) Linking ISSN: 00223069 NLM ISO Abbreviation: J Neuropathol Exp Neurol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41475018 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A novel hierarchical framework elucidating regional differences in α-synuclein and tau co-pathology in military veterans with parkinsonism. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Flores+Almazan+VG%22">Flores Almazan VG</searchLink>; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Laborc+KF%22">Laborc KF</searchLink>; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22De+Sanctis+C%22">De Sanctis C</searchLink>; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Thorn+EL%22">Thorn EL</searchLink>; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Goldstein+A%22">Goldstein A</searchLink>; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Cervera+A%22">Cervera A</searchLink>; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Quintana+Mora+DF%22">Quintana Mora DF</searchLink>; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Neurology, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Mendez+Y%22">Mendez Y</searchLink>; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Neurology, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22McGoldrick+AC%22">McGoldrick AC</searchLink>; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Neurology, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Chiu+LY%22">Chiu LY</searchLink>; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Hossain+QI%22">Hossain QI</searchLink>; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22McQuillan+S%22">McQuillan S</searchLink>; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Lind-Watson+K%22">Lind-Watson K</searchLink>; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Walker+JM%22">Walker JM</searchLink>; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, TX, United States.<br /><searchLink fieldCode="AU" term="%22Walker+RH%22">Walker RH</searchLink>; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Neurology, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Nirenberg+MJ%22">Nirenberg MJ</searchLink>; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Neurology, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Crary+JF%22">Crary JF</searchLink>; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%222985192R%22">Journal of neuropathology and experimental neurology</searchLink> [J Neuropathol Exp Neurol] 2026 Jun 01; Vol. 85 (6), pp. 525-536. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>2985192R <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1554-6578 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200223069%22">00223069 </searchLink><i>NLM ISO Abbreviation: </i>J Neuropathol Exp Neurol <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1093/jnen/nlaf137 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 525 Titles: – TitleFull: A novel hierarchical framework elucidating regional differences in α-synuclein and tau co-pathology in military veterans with parkinsonism. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Flores Almazan VG – PersonEntity: Name: NameFull: Laborc KF – PersonEntity: Name: NameFull: De Sanctis C – PersonEntity: Name: NameFull: Thorn EL – PersonEntity: Name: NameFull: Goldstein A – PersonEntity: Name: NameFull: Cervera A – PersonEntity: Name: NameFull: Quintana Mora DF – PersonEntity: Name: NameFull: Mendez Y – PersonEntity: Name: NameFull: McGoldrick AC – PersonEntity: Name: NameFull: Chiu LY – PersonEntity: Name: NameFull: Hossain QI – PersonEntity: Name: NameFull: McQuillan S – PersonEntity: Name: NameFull: Lind-Watson K – PersonEntity: Name: NameFull: Walker JM – PersonEntity: Name: NameFull: Walker RH – PersonEntity: Name: NameFull: Nirenberg MJ – PersonEntity: Name: NameFull: Crary JF IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2026 Jun 01 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1554-6578 Numbering: – Type: volume Value: 85 – Type: issue Value: 6 Titles: – TitleFull: Journal of neuropathology and experimental neurology Type: main |
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