Epigenetic biomarkers of inflammation in studies on mental health: Current applications, limitations, and future directions.

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Title: Epigenetic biomarkers of inflammation in studies on mental health: Current applications, limitations, and future directions.
Authors: Schalkwijk W; Department of Psychiatry, Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University Medical Center, Maastricht, the Netherlands. Electronic address: w.schalkwijk@umcutrecht.nl., de Witte LD; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA; Department of Human Genetics, Radboud UMC, Nijmegen, the Netherlands; Department of Psychiatry, Radboud UMC, Nijmegen, the Netherlands., Gigase FAJ; Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands; The Generation R Study Group, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Cecil CAM; Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands; The Generation R Study Group, Erasmus MC University Medical Center, Rotterdam, the Netherlands; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands; Department of Biomedical Data Sciences, Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Suderman M; Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Gülöksüz S; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University Medical Center, Maastricht, the Netherlands; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada; Institute of Mental Health, University of British Columbia, Vancouver, BC, Canada; Northern Medical Program, University of Northern BC, Prince George, BC, Canada., Rutten BPF; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University Medical Center, Maastricht, the Netherlands., Boks MP; Department of Psychiatry, Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Psychiatry, Amsterdam UMC, Amsterdam, the Netherlands; Dimence Institute for Specialized Mental Health Care, Deventer, the Netherlands.
Source: Brain, behavior, and immunity [Brain Behav Immun] 2026 Mar; Vol. 133, pp. 106245. Date of Electronic Publication: 2025 Dec 29.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Epigenetic biomarkers of inflammation in studies on mental health: Current applications, limitations, and future directions.
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  Data: <searchLink fieldCode="AU" term="%22Schalkwijk+W%22">Schalkwijk W</searchLink>; Department of Psychiatry, Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University Medical Center, Maastricht, the Netherlands. Electronic address: w.schalkwijk@umcutrecht.nl.<br /><searchLink fieldCode="AU" term="%22de+Witte+LD%22">de Witte LD</searchLink>; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA; Department of Human Genetics, Radboud UMC, Nijmegen, the Netherlands; Department of Psychiatry, Radboud UMC, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Gigase+FAJ%22">Gigase FAJ</searchLink>; Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands; The Generation R Study Group, Erasmus MC University Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Cecil+CAM%22">Cecil CAM</searchLink>; Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands; The Generation R Study Group, Erasmus MC University Medical Center, Rotterdam, the Netherlands; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands; Department of Biomedical Data Sciences, Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Suderman+M%22">Suderman M</searchLink>; Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Gülöksüz+S%22">Gülöksüz S</searchLink>; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University Medical Center, Maastricht, the Netherlands; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada; Institute of Mental Health, University of British Columbia, Vancouver, BC, Canada; Northern Medical Program, University of Northern BC, Prince George, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Rutten+BPF%22">Rutten BPF</searchLink>; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University Medical Center, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Boks+MP%22">Boks MP</searchLink>; Department of Psychiatry, Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Psychiatry, Amsterdam UMC, Amsterdam, the Netherlands; Dimence Institute for Specialized Mental Health Care, Deventer, the Netherlands.
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  Data: <searchLink fieldCode="JN" term="%228800478%22">Brain, behavior, and immunity</searchLink> [Brain Behav Immun] 2026 Mar; Vol. 133, pp. 106245. <i>Date of Electronic Publication: </i>2025 Dec 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8800478 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2139 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208891591%22">08891591 </searchLink><i>NLM ISO Abbreviation: </i>Brain Behav Immun <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bbi.2025.106245
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              Text: 2026 Mar
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