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Dynamic boronate ester crosslinked hyaluronic acid hydrogel patch enabling fast dissolution and rapid oral mucosal delivery of amorphous sumatriptan.

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Title: Dynamic boronate ester crosslinked hyaluronic acid hydrogel patch enabling fast dissolution and rapid oral mucosal delivery of amorphous sumatriptan.
Authors: Gu Z; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China., Wang J; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China., Shi X; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China., Zhou Y; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China., Chen Y; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China., He Y; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China. Electronic address: yiyanhe@njtech.edu.cn., Wu L; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China. Electronic address: lihuang.wu@njtech.edu.cn., Cui Y; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China. Electronic address: ycui@njtech.edu.cn., Gu Z; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China; Huaxi MR Research Center (HMRRC), Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, PR China.
Source: Carbohydrate polymers [Carbohydr Polym] 2026 Mar 01; Vol. 375, pp. 124751. Date of Electronic Publication: 2025 Nov 25.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 8307156 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1344 (Electronic) Linking ISSN: 01448617 NLM ISO Abbreviation: Carbohydr Polym Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dynamic boronate ester crosslinked hyaluronic acid hydrogel patch enabling fast dissolution and rapid oral mucosal delivery of amorphous sumatriptan.
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  Data: <searchLink fieldCode="AU" term="%22Gu+Z%22">Gu Z</searchLink>; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China.<br /><searchLink fieldCode="AU" term="%22Shi+X%22">Shi X</searchLink>; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China.<br /><searchLink fieldCode="AU" term="%22He+Y%22">He Y</searchLink>; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China. Electronic address: yiyanhe@njtech.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wu+L%22">Wu L</searchLink>; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China. Electronic address: lihuang.wu@njtech.edu.cn.<br /><searchLink fieldCode="AU" term="%22Cui+Y%22">Cui Y</searchLink>; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China. Electronic address: ycui@njtech.edu.cn.<br /><searchLink fieldCode="AU" term="%22Gu+Z%22">Gu Z</searchLink>; College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 211816, PR China; Sino-Spain Joint Laboratory on Biomedical Materials (S2LBM), Research Institute for Biomaterials, Tech Institute for Advanced Materials, Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Suqian Advanced Materials Industry Technology Innovation Center, Nanjing Tech University, Nanjing, 211816, PR China; Huaxi MR Research Center (HMRRC), Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, PR China.
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  Data: <searchLink fieldCode="JN" term="%228307156%22">Carbohydrate polymers</searchLink> [Carbohydr Polym] 2026 Mar 01; Vol. 375, pp. 124751. <i>Date of Electronic Publication: </i>2025 Nov 25.
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RecordInfo BibRecord:
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        Value: 10.1016/j.carbpol.2025.124751
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        Text: English
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              Text: 2026 Mar 01
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