Restoration of ovarian endocrine function with encapsulated immune-isolated human ovarian xenograft in ovariectomized mice.

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Title: Restoration of ovarian endocrine function with encapsulated immune-isolated human ovarian xenograft in ovariectomized mice.
Authors: Brunette MA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.; Division of Pediatric and Adolescent Gynecology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA., Rionda MA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Sinko D; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Machlin JH; Program in Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI, USA., Blevins GM; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Leo M; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Tan A; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Ray B; Department of Chemistry, University of Michigan, Ann Arbor, MI, USA., Cascalho M; Department of Pathology, Case Western Reserve University Cleveland, OH, USA.; Department of Microbiology & Immunology, University of Michigan, Ann Arbor, MI, USA., Padmanabhan V; Department of Pediatrics & Communicable Diseases, University of Michigan, Ann Arbor, MI, USA.; Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA., Shikanov A; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.; Program in Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI, USA.; Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA.
Source: Science advances [Sci Adv] 2026 Jan 02; Vol. 12 (1), pp. eadx6348. Date of Electronic Publication: 2026 Jan 01.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Brunette+MA%22">Brunette MA</searchLink>; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.; Division of Pediatric and Adolescent Gynecology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Rionda+MA%22">Rionda MA</searchLink>; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Sinko+D%22">Sinko D</searchLink>; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Machlin+JH%22">Machlin JH</searchLink>; Program in Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Blevins+GM%22">Blevins GM</searchLink>; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Leo+M%22">Leo M</searchLink>; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Tan+A%22">Tan A</searchLink>; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Ray+B%22">Ray B</searchLink>; Department of Chemistry, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Cascalho+M%22">Cascalho M</searchLink>; Department of Pathology, Case Western Reserve University Cleveland, OH, USA.; Department of Microbiology & Immunology, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Padmanabhan+V%22">Padmanabhan V</searchLink>; Department of Pediatrics & Communicable Diseases, University of Michigan, Ann Arbor, MI, USA.; Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Shikanov+A%22">Shikanov A</searchLink>; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.; Program in Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI, USA.; Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA.
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              Text: 2026 Jan 02
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