Association of sodium-glucose cotransporter 2 inhibitors with the risk of incident anxiety and insomnia: a retrospective cohort study using the TriNetX database.

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Title: Association of sodium-glucose cotransporter 2 inhibitors with the risk of incident anxiety and insomnia: a retrospective cohort study using the TriNetX database.
Authors: Chang CI; Department of Medical Education, Taichung Veterans General Hospital, Taichung, Taiwan., Lin JF; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan., Chen IC; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan., Lin CH; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan., Chen HH; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan., Chang MH; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan; Department of Neurology, Neurological Institute, Taichung Veterans General Hospital, Taichung, Taiwan., Tang CL; Department of Neurosurgery, Neurological Institute, Taichung Veterans General Hospital, Taichung, Taiwan. Electronic address: chienluntang@gmail.com., Pai YW; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan; Department of Neurology, Neurological Institute, Taichung Veterans General Hospital, Taichung, Taiwan. Electronic address: jasminezxcv@gmail.com.
Source: Diabetes & metabolic syndrome [Diabetes Metab Syndr] 2026 Jan; Vol. 20 (1), pp. 103373. Date of Electronic Publication: 2025 Dec 30.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Elsevier Ltd Country of Publication: Netherlands NLM ID: 101462250 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0334 (Electronic) Linking ISSN: 18714021 NLM ISO Abbreviation: Diabetes Metab Syndr Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Association of sodium-glucose cotransporter 2 inhibitors with the risk of incident anxiety and insomnia: a retrospective cohort study using the TriNetX database.
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  Data: <searchLink fieldCode="AU" term="%22Chang+CI%22">Chang CI</searchLink>; Department of Medical Education, Taichung Veterans General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+JF%22">Lin JF</searchLink>; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+IC%22">Chen IC</searchLink>; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CH%22">Lin CH</searchLink>; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+HH%22">Chen HH</searchLink>; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+MH%22">Chang MH</searchLink>; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan; Department of Neurology, Neurological Institute, Taichung Veterans General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tang+CL%22">Tang CL</searchLink>; Department of Neurosurgery, Neurological Institute, Taichung Veterans General Hospital, Taichung, Taiwan. Electronic address: chienluntang@gmail.com.<br /><searchLink fieldCode="AU" term="%22Pai+YW%22">Pai YW</searchLink>; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan; Department of Neurology, Neurological Institute, Taichung Veterans General Hospital, Taichung, Taiwan. Electronic address: jasminezxcv@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101462250%22">Diabetes & metabolic syndrome</searchLink> [Diabetes Metab Syndr] 2026 Jan; Vol. 20 (1), pp. 103373. <i>Date of Electronic Publication: </i>2025 Dec 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Ltd%22">Elsevier Ltd </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101462250 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-0334 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218714021%22">18714021 </searchLink><i>NLM ISO Abbreviation: </i>Diabetes Metab Syndr <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.dsx.2025.103373
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      – Code: eng
        Text: English
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        StartPage: 103373
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      – TitleFull: Association of sodium-glucose cotransporter 2 inhibitors with the risk of incident anxiety and insomnia: a retrospective cohort study using the TriNetX database.
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            – D: 01
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              Text: 2026 Jan
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              Y: 2026
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