ω-3 Fatty Acids in Pediatric Major Depressive Disorder: A Randomized Clinical Trial.

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Title: ω-3 Fatty Acids in Pediatric Major Depressive Disorder: A Randomized Clinical Trial.
Authors: Berger G; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland., Häberling I; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland., Emery S; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland., Albermann M; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland., Baumgartner N; Psychiatry St Gallen, Wil St Gallen, St Gallen, Switzerland., Nalani K; Department of Child and Adolescent Forensic Psychiatry, University Hospital of Psychiatry, Zurich, Switzerland., Strumberger M; Department of Clinical Research, University of Basel, Basel, Switzerland., Wöckel L; Department of Clinical Research, University of Basel, Basel, Switzerland.; Clienia Littenheid AG, Winterthur, Switzerland., Erb S; Child and Adolescent Psychiatric Services St Gallen, St Gallen, Switzerland., Bachmann S; Hôpitaux Universitaires de Genève/HUG, Geneva, Switzerland.; Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospitals Halle (Saale), Halle-Wittenburg, Germany., Müller-Knapp U; Child and Adolescent Psychiatry Klinik Sonnenhof, Ganterschwil, Switzerland., Contin-Waldvogel B; Child and Adolescent Psychiatric Services Baselland, Liestal, Switzerland., Yamini A; Child and Adolescent Psychiatric Services Thurgau, Weinfelden, Switzerland., Rhiner B; Child and Adolescent Psychiatric Services Thurgau, Weinfelden, Switzerland., Drechsler R; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland., Held U; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland., Reeve K; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland., Heinz P; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland., Pauli D; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland., Schmeck K; Department of Clinical Research, University of Basel, Basel, Switzerland., Hersberger M; Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.; Division of Clinical Chemistry and Biochemistry, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland., Walitza S; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland.; Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Federal Institute of Technology Zurich, Zurich, Switzerland.
Corporate Authors: Omega-3 pMDD Study Group
Source: JAMA network open [JAMA Netw Open] 2026 Jan 02; Vol. 9 (1), pp. e2548703. Date of Electronic Publication: 2026 Jan 02.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: ω-3 Fatty Acids in Pediatric Major Depressive Disorder: A Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Berger+G%22">Berger G</searchLink>; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Häberling+I%22">Häberling I</searchLink>; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Emery+S%22">Emery S</searchLink>; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Albermann+M%22">Albermann M</searchLink>; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Baumgartner+N%22">Baumgartner N</searchLink>; Psychiatry St Gallen, Wil St Gallen, St Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Nalani+K%22">Nalani K</searchLink>; Department of Child and Adolescent Forensic Psychiatry, University Hospital of Psychiatry, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Strumberger+M%22">Strumberger M</searchLink>; Department of Clinical Research, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wöckel+L%22">Wöckel L</searchLink>; Department of Clinical Research, University of Basel, Basel, Switzerland.; Clienia Littenheid AG, Winterthur, Switzerland.<br /><searchLink fieldCode="AU" term="%22Erb+S%22">Erb S</searchLink>; Child and Adolescent Psychiatric Services St Gallen, St Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bachmann+S%22">Bachmann S</searchLink>; Hôpitaux Universitaires de Genève/HUG, Geneva, Switzerland.; Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospitals Halle (Saale), Halle-Wittenburg, Germany.<br /><searchLink fieldCode="AU" term="%22Müller-Knapp+U%22">Müller-Knapp U</searchLink>; Child and Adolescent Psychiatry Klinik Sonnenhof, Ganterschwil, Switzerland.<br /><searchLink fieldCode="AU" term="%22Contin-Waldvogel+B%22">Contin-Waldvogel B</searchLink>; Child and Adolescent Psychiatric Services Baselland, Liestal, Switzerland.<br /><searchLink fieldCode="AU" term="%22Yamini+A%22">Yamini A</searchLink>; Child and Adolescent Psychiatric Services Thurgau, Weinfelden, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rhiner+B%22">Rhiner B</searchLink>; Child and Adolescent Psychiatric Services Thurgau, Weinfelden, Switzerland.<br /><searchLink fieldCode="AU" term="%22Drechsler+R%22">Drechsler R</searchLink>; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Held+U%22">Held U</searchLink>; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Reeve+K%22">Reeve K</searchLink>; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Heinz+P%22">Heinz P</searchLink>; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pauli+D%22">Pauli D</searchLink>; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schmeck+K%22">Schmeck K</searchLink>; Department of Clinical Research, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hersberger+M%22">Hersberger M</searchLink>; Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.; Division of Clinical Chemistry and Biochemistry, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Walitza+S%22">Walitza S</searchLink>; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland.; Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Federal Institute of Technology Zurich, Zurich, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%22101729235%22">JAMA network open</searchLink> [JAMA Netw Open] 2026 Jan 02; Vol. 9 (1), pp. e2548703. <i>Date of Electronic Publication: </i>2026 Jan 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Medical+Association%22">American Medical Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101729235 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2574-3805 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225743805%22">25743805 </searchLink><i>NLM ISO Abbreviation: </i>JAMA Netw Open <i>Subsets: </i>MEDLINE
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