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Pervasive phenotypic effects of FBXO42 are promoted by regulation of PP4 phosphatase.

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Title: Pervasive phenotypic effects of FBXO42 are promoted by regulation of PP4 phosphatase.
Authors: Yang H; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore, 308232, Singapore., Smith P; Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK., Ma Y; Tsinghua University, Beijing, China., Southworth E; Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK., Gopala Krishna V; Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK., Salerno B; Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK., Rowland J; Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK., Loftus AEP; Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK., Grieco D; DMMBM, University of Naples 'Federico II', via S. Pansini 5, 80131, Naples, Italy.; CEINGE Biotecnologie Avanzate 'Franco Salvatore', via Gaetano Salvatore 486, 80145, Naples, Italy., Vendrell I; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.; Chinese Academy for Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7FZ, UK., Fischer R; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.; Chinese Academy for Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7FZ, UK., Kessler BM; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.; Chinese Academy for Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7FZ, UK., D'Angiolella V; Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK. vdangio@ed.ac.uk.
Source: The EMBO journal [EMBO J] 2026 Feb; Vol. 45 (4), pp. 1332-1361. Date of Electronic Publication: 2026 Jan 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore, 308232, Singapore.<br /><searchLink fieldCode="AU" term="%22Smith+P%22">Smith P</searchLink>; Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Ma+Y%22">Ma Y</searchLink>; Tsinghua University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Southworth+E%22">Southworth E</searchLink>; Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Gopala+Krishna+V%22">Gopala Krishna V</searchLink>; Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Salerno+B%22">Salerno B</searchLink>; Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Rowland+J%22">Rowland J</searchLink>; Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Loftus+AEP%22">Loftus AEP</searchLink>; Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Grieco+D%22">Grieco D</searchLink>; DMMBM, University of Naples 'Federico II', via S. Pansini 5, 80131, Naples, Italy.; CEINGE Biotecnologie Avanzate 'Franco Salvatore', via Gaetano Salvatore 486, 80145, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Vendrell+I%22">Vendrell I</searchLink>; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.; Chinese Academy for Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7FZ, UK.<br /><searchLink fieldCode="AU" term="%22Fischer+R%22">Fischer R</searchLink>; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.; Chinese Academy for Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7FZ, UK.<br /><searchLink fieldCode="AU" term="%22Kessler+BM%22">Kessler BM</searchLink>; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.; Chinese Academy for Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7FZ, UK.<br /><searchLink fieldCode="AU" term="%22D'Angiolella+V%22">D'Angiolella V</searchLink>; Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK. vdangio@ed.ac.uk.
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