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Harnessing natural terpenes via PEGylated mucoadhesive vesicles for improved urinary bladder delivery: from in vitro evaluation to in vivo assessment.

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Title: Harnessing natural terpenes via PEGylated mucoadhesive vesicles for improved urinary bladder delivery: from in vitro evaluation to in vivo assessment.
Authors: Hammoodi HA; Department of Pharmacy, Mazaya University College, Thi-Qar, Iraq., Albash R; Department of Pharmaceutics, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza, Egypt., Hamed MIA; Department of Organic and Medicinal Chemistry, Faculty of Pharmacy, Fayoum University, Fayoum, Egypt., Darwish KM; Department of Medicinal Chemistry, Faculty of Pharmacy, Galala University, New Galala, Egypt.; Department of Medicinal Chemistry, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt., Kassem AB; Department of Clinical Pharmacy and Pharmacy Practice, Damnhour University, Damnhour, Egypt., Saleh A; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia., Alamoudi JA; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia., Badawi NM; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, The British University in Egypt, Cairo, Egypt.
Source: Frontiers in pharmacology [Front Pharmacol] 2025 Dec 18; Vol. 16, pp. 1685423. Date of Electronic Publication: 2025 Dec 18 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1663-9812
DOI:10.3389/fphar.2025.1685423