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A phase 2 randomized controlled trial using biologics to improve multi OIT outcomes (COMBINE): design, rationale, and methods.

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Title: A phase 2 randomized controlled trial using biologics to improve multi OIT outcomes (COMBINE): design, rationale, and methods.
Authors: Long AJ; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States., Sindher S; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States., Martinez K; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States., Choi JH; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States., Albarran M; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States., Schuetz J; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States., Parry A; Department of Pediatrics, Division of Immunology, Allergy, and Rheumatology, University of California, Los Angeles, CA, United States., Tang J; Department of Pediatrics, Division of Immunology, Allergy, and Rheumatology, University of California, Los Angeles, CA, United States., Garcia Llorett M; Department of Pediatrics, Division of Immunology, Allergy, and Rheumatology, University of California, Los Angeles, CA, United States., Zedeck SS; Department of Pediatrics, Division of Immunology, Allergy, and Rheumatology, University of California, Los Angeles, CA, United States., Grissinger A; Division of Pediatric Allergy & Immunology, University of California, San Diego, CA, United States.; Rady Children's Hospital, San Diego, CA, United States., Kiernan E; Division of Pediatric Allergy & Immunology, University of California, San Diego, CA, United States.; Rady Children's Hospital, San Diego, CA, United States., Leonard S; Division of Pediatric Allergy & Immunology, University of California, San Diego, CA, United States.; Rady Children's Hospital, San Diego, CA, United States., Raeber O; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States., Feight C; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States., Anderson B; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States., Sharma R; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States., Bogetic D; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States., Chin AR; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States., Woch M; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States., Poyser J; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States., Laurienzo Panza J; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States., Togias A; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States., Wheatley L; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States., Boyd S; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States., Galli SJ; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States.; Departments of Pathology and of Microbiology and Immunology, Stanford University, Stanford, CA, United States., Nadeau KC; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, United States., Chinthrajah RS; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States.
Source: Frontiers in allergy [Front Allergy] 2025 Dec 18; Vol. 6, pp. 1729111. Date of Electronic Publication: 2025 Dec 18 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 9918227355906676 Publication Model: eCollection Cited Medium: Internet ISSN: 2673-6101 (Electronic) Linking ISSN: 26736101 NLM ISO Abbreviation: Front Allergy Subsets: PubMed not MEDLINE
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  Data: A phase 2 randomized controlled trial using biologics to improve multi OIT outcomes (COMBINE): design, rationale, and methods.
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Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States.<br /><searchLink fieldCode="AU" term="%22Parry+A%22">Parry A</searchLink>; Department of Pediatrics, Division of Immunology, Allergy, and Rheumatology, University of California, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Tang+J%22">Tang J</searchLink>; Department of Pediatrics, Division of Immunology, Allergy, and Rheumatology, University of California, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Garcia+Llorett+M%22">Garcia Llorett M</searchLink>; Department of Pediatrics, Division of Immunology, Allergy, and Rheumatology, University of California, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Zedeck+SS%22">Zedeck SS</searchLink>; Department of Pediatrics, Division of Immunology, Allergy, and Rheumatology, University of California, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Grissinger+A%22">Grissinger A</searchLink>; Division of Pediatric Allergy & Immunology, University of California, San Diego, CA, United States.; Rady Children's Hospital, San Diego, CA, United States.<br /><searchLink fieldCode="AU" term="%22Kiernan+E%22">Kiernan E</searchLink>; Division of Pediatric Allergy & Immunology, University of California, San Diego, CA, United States.; Rady Children's Hospital, San Diego, CA, United States.<br /><searchLink fieldCode="AU" term="%22Leonard+S%22">Leonard S</searchLink>; Division of Pediatric Allergy & Immunology, University of California, San Diego, CA, United States.; Rady Children's Hospital, San Diego, CA, United States.<br /><searchLink fieldCode="AU" term="%22Raeber+O%22">Raeber O</searchLink>; Department of Pathology, Sean N. 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Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States.<br /><searchLink fieldCode="AU" term="%22Galli+SJ%22">Galli SJ</searchLink>; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States.; Departments of Pathology and of Microbiology and Immunology, Stanford University, Stanford, CA, United States.<br /><searchLink fieldCode="AU" term="%22Nadeau+KC%22">Nadeau KC</searchLink>; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Chinthrajah+RS%22">Chinthrajah RS</searchLink>; Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States.
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  Data: <searchLink fieldCode="JN" term="%229918227355906676%22">Frontiers in allergy</searchLink> [Front Allergy] 2025 Dec 18; Vol. 6, pp. 1729111. <i>Date of Electronic Publication: </i>2025 Dec 18 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media+S%2EA%22">Frontiers Media S.A </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>9918227355906676 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2673-6101 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226736101%22">26736101 </searchLink><i>NLM ISO Abbreviation: </i>Front Allergy <i>Subsets: </i>PubMed not MEDLINE
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