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Development and International Validation of a Novel Imaging-Based Risk Score (IsCHEMiA) for the Prediction of Poststroke Epilepsy.

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Title: Development and International Validation of a Novel Imaging-Based Risk Score (IsCHEMiA) for the Prediction of Poststroke Epilepsy.
Authors: Leung WCY; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston.; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China., Tanaka T; Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan., Donahue RA; Neurology Clinical Research Institute, Massachusetts General Hospital, Boston., Chan KCW; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China., Wang J; Massachusetts General Biostatistics, Harvard Medical School, Boston., Chung THF; Department of Psychology, University of Hong Kong, China., Wong YK; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China., Liu KCR; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China., Leung IYH; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China., Ho RW; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China., Chu FHN; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China., Leung AKL; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China., Teo KC; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China., Pang SYY; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China., Yip EK; Department of Medicine and Geriatrics, Ruttonjee Hospital, Hong Kong SAR, China., Ihara M; Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan., Fukuma K; Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan., Reeder HT; Massachusetts General Biostatistics, Harvard Medical School, Boston., Chibnik LB; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston.; Neurology Clinical Research Institute, Massachusetts General Hospital, Boston., Cole AJ; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston., Lau GKK; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China.; Tam Wing Fan Neuroimaging Research Laboratory, Li Ka Shing Faculty of Medicine, University of Hong Kong, China; and.; State Key Laboratory of Brain and Cognitive Sciences, University of Hong Kong, China., Singhal AB; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston.
Source: Neurology [Neurology] 2026 Jan 27; Vol. 106 (2), pp. e214486. Date of Electronic Publication: 2026 Jan 05.
Publication Type: Journal Article; Validation Study
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-632X (Electronic) Linking ISSN: 00283878 NLM ISO Abbreviation: Neurology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Development and International Validation of a Novel Imaging-Based Risk Score (IsCHEMiA) for the Prediction of Poststroke Epilepsy.
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  Data: <searchLink fieldCode="AU" term="%22Leung+WCY%22">Leung WCY</searchLink>; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston.; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Tanaka+T%22">Tanaka T</searchLink>; Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Donahue+RA%22">Donahue RA</searchLink>; Neurology Clinical Research Institute, Massachusetts General Hospital, Boston.<br /><searchLink fieldCode="AU" term="%22Chan+KCW%22">Chan KCW</searchLink>; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Massachusetts General Biostatistics, Harvard Medical School, Boston.<br /><searchLink fieldCode="AU" term="%22Chung+THF%22">Chung THF</searchLink>; Department of Psychology, University of Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Wong+YK%22">Wong YK</searchLink>; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Liu+KCR%22">Liu KCR</searchLink>; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Leung+IYH%22">Leung IYH</searchLink>; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Ho+RW%22">Ho RW</searchLink>; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Chu+FHN%22">Chu FHN</searchLink>; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Leung+AKL%22">Leung AKL</searchLink>; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Teo+KC%22">Teo KC</searchLink>; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Pang+SYY%22">Pang SYY</searchLink>; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Yip+EK%22">Yip EK</searchLink>; Department of Medicine and Geriatrics, Ruttonjee Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Ihara+M%22">Ihara M</searchLink>; Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Fukuma+K%22">Fukuma K</searchLink>; Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Reeder+HT%22">Reeder HT</searchLink>; Massachusetts General Biostatistics, Harvard Medical School, Boston.<br /><searchLink fieldCode="AU" term="%22Chibnik+LB%22">Chibnik LB</searchLink>; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston.; Neurology Clinical Research Institute, Massachusetts General Hospital, Boston.<br /><searchLink fieldCode="AU" term="%22Cole+AJ%22">Cole AJ</searchLink>; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston.<br /><searchLink fieldCode="AU" term="%22Lau+GKK%22">Lau GKK</searchLink>; Division of Neurology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, China.; Tam Wing Fan Neuroimaging Research Laboratory, Li Ka Shing Faculty of Medicine, University of Hong Kong, China; and.; State Key Laboratory of Brain and Cognitive Sciences, University of Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Singhal+AB%22">Singhal AB</searchLink>; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston.
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  Data: <searchLink fieldCode="JN" term="%220401060%22">Neurology</searchLink> [Neurology] 2026 Jan 27; Vol. 106 (2), pp. e214486. <i>Date of Electronic Publication: </i>2026 Jan 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0401060 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1526-632X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200283878%22">00283878 </searchLink><i>NLM ISO Abbreviation: </i>Neurology <i>Subsets: </i>MEDLINE
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        Value: 10.1212/WNL.0000000000214486
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        Text: English
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              Text: 2026 Jan 27
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