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Function and regulation of the CD163-HO-1 pathway in hemin-differentiated macrophages from patients with abdominal aortic aneurysm.

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Title: Function and regulation of the CD163-HO-1 pathway in hemin-differentiated macrophages from patients with abdominal aortic aneurysm.
Authors: Hamann B; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany., Weinert S; Multi-parametric Bioimaging and Cytometry (MPBIC) Core Facility, University Hospital, Otto-von-Guericke-University, Magdeburg, Germany., Mittag J; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany., Poitz DM; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany., Frank F; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany., Kränkel N; Department of Cardiology, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany., Kapalla M; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany., Kopaliani I; Institute for Physiology, Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany., Langner M; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany., Peitzsch M; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany., Klimova A; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a Partnership Between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, And Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Germany; Institute for Medical Informatics and Biometry, University Carl Gustav Carus and Medical Faculty, Technische Universität Dresden, Dresden, Germany., Klotz F; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany., Reeps C; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany., Hofmann A; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany. Electronic address: anja.hofmann2@uniklinikum-dresden.de.
Source: Free radical biology & medicine [Free Radic Biol Med] 2026 Mar 01; Vol. 245, pp. 418-432. Date of Electronic Publication: 2026 Jan 03.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Hamann+B%22">Hamann B</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany.<br /><searchLink fieldCode="AU" term="%22Weinert+S%22">Weinert S</searchLink>; Multi-parametric Bioimaging and Cytometry (MPBIC) Core Facility, University Hospital, Otto-von-Guericke-University, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Mittag+J%22">Mittag J</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany.<br /><searchLink fieldCode="AU" term="%22Poitz+DM%22">Poitz DM</searchLink>; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany.<br /><searchLink fieldCode="AU" term="%22Frank+F%22">Frank F</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany.<br /><searchLink fieldCode="AU" term="%22Kränkel+N%22">Kränkel N</searchLink>; Department of Cardiology, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Kapalla+M%22">Kapalla M</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany.<br /><searchLink fieldCode="AU" term="%22Kopaliani+I%22">Kopaliani I</searchLink>; Institute for Physiology, Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany.<br /><searchLink fieldCode="AU" term="%22Langner+M%22">Langner M</searchLink>; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany.<br /><searchLink fieldCode="AU" term="%22Peitzsch+M%22">Peitzsch M</searchLink>; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany.<br /><searchLink fieldCode="AU" term="%22Klimova+A%22">Klimova A</searchLink>; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a Partnership Between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, And Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Germany; Institute for Medical Informatics and Biometry, University Carl Gustav Carus and Medical Faculty, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Klotz+F%22">Klotz F</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany.<br /><searchLink fieldCode="AU" term="%22Reeps+C%22">Reeps C</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany.<br /><searchLink fieldCode="AU" term="%22Hofmann+A%22">Hofmann A</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Germany. Electronic address: anja.hofmann2@uniklinikum-dresden.de.
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