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Prognostic impact of co-occurring FLT3 mutations across molecular subgroups in intensively treated acute myeloid leukemia: insights from real-world genomic data.

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Title: Prognostic impact of co-occurring FLT3 mutations across molecular subgroups in intensively treated acute myeloid leukemia: insights from real-world genomic data.
Authors: Chang YS; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan., Tien FM; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan., Wang YW; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan., Yao CY; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan., Tsai XC; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Ni SC; Department of Hematological Oncology, National Taiwan University Cancer Center, Taipei, Taiwan., Lo MY; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan., Lee WH; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsin-Chu, Taiwan., Lin CC; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan., Kuo YY; Tai-Chen Cell Therapy Center, National Taiwan University, Taipei, Taiwan., Peng YL; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Tseng MH; Tai-Chen Cell Therapy Center, National Taiwan University, Taipei, Taiwan., Ko BS; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Hematological Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.; Tai-Chen Cell Therapy Center, National Taiwan University, Taipei, Taiwan., Yao M; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Division of cellular therapy, Department of Integrated Diagnostics & Therapeutics, National Taiwan University Hospital, Taipei, Taiwan., Tien HF; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, Far-Eastern Memorial Hospital, New Taipei City, Taiwan., Hou HA; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. hsinanhou@ntu.edu.tw.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan. hsinanhou@ntu.edu.tw.; Division of General Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. hsinanhou@ntu.edu.tw., Chou WC; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Source: Blood cancer journal [Blood Cancer J] 2026 Jan 06; Vol. 16 (1), pp. 3. Date of Electronic Publication: 2026 Jan 06.
Publication Type: Letter
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101568469 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-5385 (Electronic) Linking ISSN: 20445385 NLM ISO Abbreviation: Blood Cancer J Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Prognostic impact of co-occurring FLT3 mutations across molecular subgroups in intensively treated acute myeloid leukemia: insights from real-world genomic data.
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  Data: <searchLink fieldCode="AU" term="%22Chang+YS%22">Chang YS</searchLink>; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tien+FM%22">Tien FM</searchLink>; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+YW%22">Wang YW</searchLink>; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yao+CY%22">Yao CY</searchLink>; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+XC%22">Tsai XC</searchLink>; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ni+SC%22">Ni SC</searchLink>; Department of Hematological Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lo+MY%22">Lo MY</searchLink>; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+WH%22">Lee WH</searchLink>; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsin-Chu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CC%22">Lin CC</searchLink>; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+YY%22">Kuo YY</searchLink>; Tai-Chen Cell Therapy Center, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Peng+YL%22">Peng YL</searchLink>; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tseng+MH%22">Tseng MH</searchLink>; Tai-Chen Cell Therapy Center, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ko+BS%22">Ko BS</searchLink>; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Hematological Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.; Tai-Chen Cell Therapy Center, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yao+M%22">Yao M</searchLink>; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Division of cellular therapy, Department of Integrated Diagnostics & Therapeutics, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tien+HF%22">Tien HF</searchLink>; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, Far-Eastern Memorial Hospital, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hou+HA%22">Hou HA</searchLink>; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. hsinanhou@ntu.edu.tw.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan. hsinanhou@ntu.edu.tw.; Division of General Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. hsinanhou@ntu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Chou+WC%22">Chou WC</searchLink>; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101568469%22">Blood cancer journal</searchLink> [Blood Cancer J] 2026 Jan 06; Vol. 16 (1), pp. 3. <i>Date of Electronic Publication: </i>2026 Jan 06.
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