Vascularized human brain organoids as a model of the brain-peripheral axis in HIV-1 neuropathogenesis.

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Title: Vascularized human brain organoids as a model of the brain-peripheral axis in HIV-1 neuropathogenesis.
Authors: Selvam S; Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, 2117 Pitt Public Health, 130 DeSoto Street, Pittsburgh, PA, 15260, USA., Dos Reis RS; Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, 2117 Pitt Public Health, 130 DeSoto Street, Pittsburgh, PA, 15260, USA., Wagner MCE; Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, 2117 Pitt Public Health, 130 DeSoto Street, Pittsburgh, PA, 15260, USA., Krishnakumar R; Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, 2117 Pitt Public Health, 130 DeSoto Street, Pittsburgh, PA, 15260, USA., Keshavarz K; Department of Pathology, Division of Experimental Pathology School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15260, USA., Ebrahimkhani MR; Department of Pathology, Division of Experimental Pathology School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15260, USA., Ayyavoo V; Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, 2117 Pitt Public Health, 130 DeSoto Street, Pittsburgh, PA, 15260, USA. Velpandi@pitt.edu.
Source: Scientific reports [Sci Rep] 2026 Jan 05; Vol. 16 (1), pp. 3794. Date of Electronic Publication: 2026 Jan 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Selvam+S%22">Selvam S</searchLink>; Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, 2117 Pitt Public Health, 130 DeSoto Street, Pittsburgh, PA, 15260, USA.<br /><searchLink fieldCode="AU" term="%22Dos+Reis+RS%22">Dos Reis RS</searchLink>; Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, 2117 Pitt Public Health, 130 DeSoto Street, Pittsburgh, PA, 15260, USA.<br /><searchLink fieldCode="AU" term="%22Wagner+MCE%22">Wagner MCE</searchLink>; Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, 2117 Pitt Public Health, 130 DeSoto Street, Pittsburgh, PA, 15260, USA.<br /><searchLink fieldCode="AU" term="%22Krishnakumar+R%22">Krishnakumar R</searchLink>; Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, 2117 Pitt Public Health, 130 DeSoto Street, Pittsburgh, PA, 15260, USA.<br /><searchLink fieldCode="AU" term="%22Keshavarz+K%22">Keshavarz K</searchLink>; Department of Pathology, Division of Experimental Pathology School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15260, USA.<br /><searchLink fieldCode="AU" term="%22Ebrahimkhani+MR%22">Ebrahimkhani MR</searchLink>; Department of Pathology, Division of Experimental Pathology School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15260, USA.<br /><searchLink fieldCode="AU" term="%22Ayyavoo+V%22">Ayyavoo V</searchLink>; Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, 2117 Pitt Public Health, 130 DeSoto Street, Pittsburgh, PA, 15260, USA. Velpandi@pitt.edu.
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        Value: 10.1038/s41598-025-33940-5
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              Text: 2026 Jan 05
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