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Genetic ancestry proportion influences risk of adverse events from tuberculosis treatment in Brazil.

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Title: Genetic ancestry proportion influences risk of adverse events from tuberculosis treatment in Brazil.
Authors: Piekos JA; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biomedical Informatics, Vanderbilt University Medical Center, 2525 West End Ave, Suite 1150, Nashville, TN, 37027, USA.; Division of Quantitative and Clinical Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA., Amorim G; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Ridolfi F; Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.; Division of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Cordeiro-Santos M; Fundação Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brazil.; Universidade do Estado do Amazonas (UEA), Manaus, Brazil., Kritski AL; Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Figueiredo MC; Division of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Andrade BB; Multinational Organization Network Sponsoring Translational and Epidemiological Research (MONSTER) Initiative, Bahia, Brazil.; Instituto Brasileiro Para Investigação da Tuberculose, Fundação Jose Silveira, Salvador, Bahia, Brazil.; Instituto Goncalo Moniz, Fundação Oswaldo Cruz, Salvador, Bahia, Brazil.; Escola Bahiana de Medicina e Saúde Publica (EBMSP), Salvador, Bahia, Brazil.; Universidade Salvador (UNIFACS), Laureate Universities, Salvador, Bahia, Brazil.; Faculdade de Tecnologia e Ciências (FTC), Salvador, Bahia, Brazil., Santos AR; Laboratory of Molecular Biology Applied to Mycobacteria, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil., Haas DW; Division of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Internal Medicine, Meharry Medical College, Nashville, TN, USA., Sterling TR; Division of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Rolla VC; Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil., Velez Edwards DR; Department of Biomedical Informatics, Vanderbilt University Medical Center, 2525 West End Ave, Suite 1150, Nashville, TN, 37027, USA. digna.r.velez.edwards@vumc.org.; Division of Quantitative and Clinical Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA. digna.r.velez.edwards@vumc.org.
Corporate Authors: Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil consortium
Source: Human genetics [Hum Genet] 2026 Jan 06; Vol. 145 (1), pp. 10. Date of Electronic Publication: 2026 Jan 06.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7613873 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1203 (Electronic) Linking ISSN: 03406717 NLM ISO Abbreviation: Hum Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genetic ancestry proportion influences risk of adverse events from tuberculosis treatment in Brazil.
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  Data: <searchLink fieldCode="AU" term="%22Piekos+JA%22">Piekos JA</searchLink>; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biomedical Informatics, Vanderbilt University Medical Center, 2525 West End Ave, Suite 1150, Nashville, TN, 37027, USA.; Division of Quantitative and Clinical Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Amorim+G%22">Amorim G</searchLink>; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Ridolfi+F%22">Ridolfi F</searchLink>; Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.; Division of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Cordeiro-Santos+M%22">Cordeiro-Santos M</searchLink>; Fundação Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brazil.; Universidade do Estado do Amazonas (UEA), Manaus, Brazil.<br /><searchLink fieldCode="AU" term="%22Kritski+AL%22">Kritski AL</searchLink>; Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Figueiredo+MC%22">Figueiredo MC</searchLink>; Division of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Andrade+BB%22">Andrade BB</searchLink>; Multinational Organization Network Sponsoring Translational and Epidemiological Research (MONSTER) Initiative, Bahia, Brazil.; Instituto Brasileiro Para Investigação da Tuberculose, Fundação Jose Silveira, Salvador, Bahia, Brazil.; Instituto Goncalo Moniz, Fundação Oswaldo Cruz, Salvador, Bahia, Brazil.; Escola Bahiana de Medicina e Saúde Publica (EBMSP), Salvador, Bahia, Brazil.; Universidade Salvador (UNIFACS), Laureate Universities, Salvador, Bahia, Brazil.; Faculdade de Tecnologia e Ciências (FTC), Salvador, Bahia, Brazil.<br /><searchLink fieldCode="AU" term="%22Santos+AR%22">Santos AR</searchLink>; Laboratory of Molecular Biology Applied to Mycobacteria, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Haas+DW%22">Haas DW</searchLink>; Division of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Internal Medicine, Meharry Medical College, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Sterling+TR%22">Sterling TR</searchLink>; Division of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Rolla+VC%22">Rolla VC</searchLink>; Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Velez+Edwards+DR%22">Velez Edwards DR</searchLink>; Department of Biomedical Informatics, Vanderbilt University Medical Center, 2525 West End Ave, Suite 1150, Nashville, TN, 37027, USA. digna.r.velez.edwards@vumc.org.; Division of Quantitative and Clinical Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA. digna.r.velez.edwards@vumc.org.
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  Data: <searchLink fieldCode="CA" term="%22Regional+Prospective+Observational+Research+in+Tuberculosis+%28RePORT%29-Brazil+consortium%22">Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil consortium</searchLink>
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  Data: <searchLink fieldCode="JN" term="%227613873%22">Human genetics</searchLink> [Hum Genet] 2026 Jan 06; Vol. 145 (1), pp. 10. <i>Date of Electronic Publication: </i>2026 Jan 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>7613873 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203406717%22">03406717 </searchLink><i>NLM ISO Abbreviation: </i>Hum Genet <i>Subsets: </i>MEDLINE
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