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Microscale Thermophoresis for Thermodynamic Analysis: A Proof-of-Concept Study on LIMK Inhibitors.

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Title: Microscale Thermophoresis for Thermodynamic Analysis: A Proof-of-Concept Study on LIMK Inhibitors.
Authors: Chartier S; Institut de Chimie Organique et Analytique (ICOA), CNRS FR 2708 - UMR 7311, Université d'Orléans 45067 Orléans, France., Claude B; Institut de Chimie Organique et Analytique (ICOA), CNRS FR 2708 - UMR 7311, Université d'Orléans 45067 Orléans, France., Nasreddine R; Institut de Chimie Organique et Analytique (ICOA), CNRS FR 2708 - UMR 7311, Université d'Orléans 45067 Orléans, France., Soule P; Application Team, NanoTemper Technologies GmbH, Munich, Germany., Launay A; Institut de Chimie Organique et Analytique (ICOA), CNRS FR 2708 - UMR 7311, Université d'Orléans 45067 Orléans, France., Rapeto M; Centre de Biophysique Moléculaire, UPR4301, CNRS-Université d'Orléans, 45071 Orléans Cedex 2, France., Villalonga-Rosso E; Centre de Biophysique Moléculaire, UPR4301, CNRS-Université d'Orléans, 45071 Orléans Cedex 2, France., Vallée B; Centre de Biophysique Moléculaire, UPR4301, CNRS-Université d'Orléans, 45071 Orléans Cedex 2, France., Sebban M; Institut CARMeN (UMR 6064), Univ Rouen Normandie, INSA Rouen Normandie, Univ Caen Normandie, ENSICAEN, CNRS, Rouen, F-76000, France., Coadou G; Institut CARMeN (UMR 6064), Univ Rouen Normandie, INSA Rouen Normandie, Univ Caen Normandie, ENSICAEN, CNRS, Rouen, F-76000, France., Nehmé R; Institut de Chimie Organique et Analytique (ICOA), CNRS FR 2708 - UMR 7311, Université d'Orléans 45067 Orléans, France. Electronic address: reine.nehme@univ-orleans.fr.
Source: Journal of molecular biology [J Mol Biol] 2026 Mar 01; Vol. 438 (5), pp. 169621. Date of Electronic Publication: 2026 Jan 04.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8638 (Electronic) Linking ISSN: 00222836 NLM ISO Abbreviation: J Mol Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Microscale Thermophoresis for Thermodynamic Analysis: A Proof-of-Concept Study on LIMK Inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Chartier+S%22">Chartier S</searchLink>; Institut de Chimie Organique et Analytique (ICOA), CNRS FR 2708 - UMR 7311, Université d'Orléans 45067 Orléans, France.<br /><searchLink fieldCode="AU" term="%22Claude+B%22">Claude B</searchLink>; Institut de Chimie Organique et Analytique (ICOA), CNRS FR 2708 - UMR 7311, Université d'Orléans 45067 Orléans, France.<br /><searchLink fieldCode="AU" term="%22Nasreddine+R%22">Nasreddine R</searchLink>; Institut de Chimie Organique et Analytique (ICOA), CNRS FR 2708 - UMR 7311, Université d'Orléans 45067 Orléans, France.<br /><searchLink fieldCode="AU" term="%22Soule+P%22">Soule P</searchLink>; Application Team, NanoTemper Technologies GmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Launay+A%22">Launay A</searchLink>; Institut de Chimie Organique et Analytique (ICOA), CNRS FR 2708 - UMR 7311, Université d'Orléans 45067 Orléans, France.<br /><searchLink fieldCode="AU" term="%22Rapeto+M%22">Rapeto M</searchLink>; Centre de Biophysique Moléculaire, UPR4301, CNRS-Université d'Orléans, 45071 Orléans Cedex 2, France.<br /><searchLink fieldCode="AU" term="%22Villalonga-Rosso+E%22">Villalonga-Rosso E</searchLink>; Centre de Biophysique Moléculaire, UPR4301, CNRS-Université d'Orléans, 45071 Orléans Cedex 2, France.<br /><searchLink fieldCode="AU" term="%22Vallée+B%22">Vallée B</searchLink>; Centre de Biophysique Moléculaire, UPR4301, CNRS-Université d'Orléans, 45071 Orléans Cedex 2, France.<br /><searchLink fieldCode="AU" term="%22Sebban+M%22">Sebban M</searchLink>; Institut CARMeN (UMR 6064), Univ Rouen Normandie, INSA Rouen Normandie, Univ Caen Normandie, ENSICAEN, CNRS, Rouen, F-76000, France.<br /><searchLink fieldCode="AU" term="%22Coadou+G%22">Coadou G</searchLink>; Institut CARMeN (UMR 6064), Univ Rouen Normandie, INSA Rouen Normandie, Univ Caen Normandie, ENSICAEN, CNRS, Rouen, F-76000, France.<br /><searchLink fieldCode="AU" term="%22Nehmé+R%22">Nehmé R</searchLink>; Institut de Chimie Organique et Analytique (ICOA), CNRS FR 2708 - UMR 7311, Université d'Orléans 45067 Orléans, France. Electronic address: reine.nehme@univ-orleans.fr.
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  Data: <searchLink fieldCode="JN" term="%222985088R%22">Journal of molecular biology</searchLink> [J Mol Biol] 2026 Mar 01; Vol. 438 (5), pp. 169621. <i>Date of Electronic Publication: </i>2026 Jan 04.
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