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Advances in BRET probes for intracellular target engagement studies.

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Title: Advances in BRET probes for intracellular target engagement studies.
Authors: Capener JL; Structural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Schwalm MP; Promega, Madison, WI, USA., Vasta JD; Promega, Madison, WI, USA., Michaud A; Promega, Madison, WI, USA., Teske KA; Promega, Madison, WI, USA., Marsiglia WM; University of Alabama at Birmingham, Birmingham, AL, USA., Huber KVM; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Dar AC; Program in Chemical Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Knapp S; Institute for Pharmaceutical Chemistry, Johann Wolfgang Goethe University, Frankfurt am Main, Germany. knapp@pharmchem.uni-frankfurt.de.; Structural Genomics Consortium (SGC), Buchmann Institute for Life Sciences, Frankfurt am Main, Germany. knapp@pharmchem.uni-frankfurt.de.; German Cancer Consortium (DKTK)/German Cancer Research Center (DKFZ), DTKT Site Frankfurt-Mainz, Heidelberg, Germany. knapp@pharmchem.uni-frankfurt.de., Axtman AD; Structural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. alison.axtman@unc.edu., Robers MB; Promega, Madison, WI, USA. matt.robers@promega.com.
Source: Nature chemical biology [Nat Chem Biol] 2026 May; Vol. 22 (5), pp. 691-701. Date of Electronic Publication: 2026 Jan 06.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Advances in BRET probes for intracellular target engagement studies.
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  Data: <searchLink fieldCode="AU" term="%22Capener+JL%22">Capener JL</searchLink>; Structural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Schwalm+MP%22">Schwalm MP</searchLink>; Promega, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Vasta+JD%22">Vasta JD</searchLink>; Promega, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Michaud+A%22">Michaud A</searchLink>; Promega, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Teske+KA%22">Teske KA</searchLink>; Promega, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Marsiglia+WM%22">Marsiglia WM</searchLink>; University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Huber+KVM%22">Huber KVM</searchLink>; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Dar+AC%22">Dar AC</searchLink>; Program in Chemical Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Knapp+S%22">Knapp S</searchLink>; Institute for Pharmaceutical Chemistry, Johann Wolfgang Goethe University, Frankfurt am Main, Germany. knapp@pharmchem.uni-frankfurt.de.; Structural Genomics Consortium (SGC), Buchmann Institute for Life Sciences, Frankfurt am Main, Germany. knapp@pharmchem.uni-frankfurt.de.; German Cancer Consortium (DKTK)/German Cancer Research Center (DKFZ), DTKT Site Frankfurt-Mainz, Heidelberg, Germany. knapp@pharmchem.uni-frankfurt.de.<br /><searchLink fieldCode="AU" term="%22Axtman+AD%22">Axtman AD</searchLink>; Structural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. alison.axtman@unc.edu.<br /><searchLink fieldCode="AU" term="%22Robers+MB%22">Robers MB</searchLink>; Promega, Madison, WI, USA. matt.robers@promega.com.
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  Data: <searchLink fieldCode="JN" term="%22101231976%22">Nature chemical biology</searchLink> [Nat Chem Biol] 2026 May; Vol. 22 (5), pp. 691-701. <i>Date of Electronic Publication: </i>2026 Jan 06.
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              Text: 2026 May
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