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IL10R Inhibition Induces Neutrophil Tumoricidal Activity.

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Title: IL10R Inhibition Induces Neutrophil Tumoricidal Activity.
Authors: Khalil DN; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York., Gomez R; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York., Regev A; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York.; Parker Institute for Cancer Immunotherapy and Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York., Samaan F; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York., Marouf Y; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York.; Parker Institute for Cancer Immunotherapy and Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York., Budhu S; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York.; Parker Institute for Cancer Immunotherapy and Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York., Hirschhorn D; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York.; Parker Institute for Cancer Immunotherapy and Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York., Schulze I; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York.; Parker Institute for Cancer Immunotherapy and Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York., Lavery JA; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York., Ceglia N; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York., Freeman SS; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York., Maltez VI; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland., Garcia JM; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland., Suek N; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York., Weng CH; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York.; Parker Institute for Cancer Immunotherapy and Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York., Cabanski CR; Parker Institute for Cancer Immunotherapy , San Francisco, California., Monette S; Laboratory of Comparative Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medicine , New York, New York.; The Rockefeller University, New York, New York., Romin Y; Molecular Cytology Facility, Memorial Sloan Kettering Cancer Center, New York, New York., Li Y; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York., Chaligne R; Computational & Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York., Yellin MJ; Celldex Therapeutics , Hampton, New Jersey., Keler T; Celldex Therapeutics , Hampton, New Jersey., Maurer DM; Celldex Therapeutics , Hampton, New Jersey., Flamar AL; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York., Morgado-Palacin L; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York.; Parker Institute for Cancer Immunotherapy and Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York., Mangarin LM; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York.; Parker Institute for Cancer Immunotherapy and Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York., Harding JJ; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medicine , New York, New York., Park W; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medicine , New York, New York., Lyman JP; The Lustgarten Foundation , Uniondale, New York., Maddock S; Parker Institute for Cancer Immunotherapy , San Francisco, California., O'Hara MH; Parker Institute for Cancer Immunotherapy , San Francisco, California.; Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania., Abou-Alfa GK; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medicine , New York, New York.; Trinity College Dublin, Dublin, Ireland., Vonderheide RH; Parker Institute for Cancer Immunotherapy , San Francisco, California.; Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania., O'Reilly EM; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medicine , New York, New York., Germain RN; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland., Wolchok JD; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York.; Parker Institute for Cancer Immunotherapy and Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York.; Department of Medicine, Weill Cornell Medicine, New York, New York., Merghoub T; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York.; Parker Institute for Cancer Immunotherapy and Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York.
Source: Cancer immunology research [Cancer Immunol Res] 2026 May 04; Vol. 14 (5), pp. 733-750.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE
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Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Morgado-Palacin+L%22">Morgado-Palacin L</searchLink>; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York.; Parker Institute for Cancer Immunotherapy and Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Mangarin+LM%22">Mangarin LM</searchLink>; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York.; Parker Institute for Cancer Immunotherapy and Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Harding+JJ%22">Harding JJ</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medicine , New York, New York.<br /><searchLink fieldCode="AU" term="%22Park+W%22">Park W</searchLink>; 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Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, New York.; Parker Institute for Cancer Immunotherapy and Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York.
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