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Inhibition of HDAC6 promotes in vitro maturation of Tan sheep oocytes by bidirectionally and synergistically regulating EGFR/CNP expression via histone acetylation.

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Title: Inhibition of HDAC6 promotes in vitro maturation of Tan sheep oocytes by bidirectionally and synergistically regulating EGFR/CNP expression via histone acetylation.
Authors: Yan Y; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China., Lv D; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China., Qi Z; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China., Wang X; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China., Wang J; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China., Song H; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China., He J; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China., Min S; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China., Chen Q; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China. Electronic address: chenqiang@nxu.edu.cn., Liu X; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China. Electronic address: liu2019074@nxu.edu.cn.
Source: Theriogenology [Theriogenology] 2026 Apr 01; Vol. 254, pp. 117797. Date of Electronic Publication: 2025 Dec 29.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0421510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3231 (Electronic) Linking ISSN: 0093691X NLM ISO Abbreviation: Theriogenology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Inhibition of HDAC6 promotes in vitro maturation of Tan sheep oocytes by bidirectionally and synergistically regulating EGFR/CNP expression via histone acetylation.
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  Data: <searchLink fieldCode="AU" term="%22Yan+Y%22">Yan Y</searchLink>; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China.<br /><searchLink fieldCode="AU" term="%22Lv+D%22">Lv D</searchLink>; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China.<br /><searchLink fieldCode="AU" term="%22Qi+Z%22">Qi Z</searchLink>; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China.<br /><searchLink fieldCode="AU" term="%22Song+H%22">Song H</searchLink>; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China.<br /><searchLink fieldCode="AU" term="%22He+J%22">He J</searchLink>; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China.<br /><searchLink fieldCode="AU" term="%22Min+S%22">Min S</searchLink>; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China.<br /><searchLink fieldCode="AU" term="%22Chen+Q%22">Chen Q</searchLink>; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China. Electronic address: chenqiang@nxu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, Ningxia University, Yinchuan, Ningxia, 750021, China; School of Life Sciences, Ningxia University, Yinchuan, Ningxia, 750021, China. Electronic address: liu2019074@nxu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%220421510%22">Theriogenology</searchLink> [Theriogenology] 2026 Apr 01; Vol. 254, pp. 117797. <i>Date of Electronic Publication: </i>2025 Dec 29.
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        Value: 10.1016/j.theriogenology.2025.117797
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      – Code: eng
        Text: English
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        StartPage: 117797
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      – TitleFull: Inhibition of HDAC6 promotes in vitro maturation of Tan sheep oocytes by bidirectionally and synergistically regulating EGFR/CNP expression via histone acetylation.
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            – D: 01
              M: 04
              Text: 2026 Apr 01
              Type: published
              Y: 2026
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              Value: 254
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