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Hepatocyte-Derived Exosomes Reduce Hepatic Ischemia-Reperfusion (IR) Injury by Inhibiting Complement Activation.

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Title: Hepatocyte-Derived Exosomes Reduce Hepatic Ischemia-Reperfusion (IR) Injury by Inhibiting Complement Activation.
Authors: Yang Z; Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; Guangxi Health Commission Key Laboratory of Basic Research in Sphingolipid Metabolism Related Diseases, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; China-USA Lipids in Health and Disease Research Center, Guilin Medical University, 541001 Guilin, Guangxi, China.; Laboratory of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China., Deng B; Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; Guangxi Health Commission Key Laboratory of Basic Research in Sphingolipid Metabolism Related Diseases, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; China-USA Lipids in Health and Disease Research Center, Guilin Medical University, 541001 Guilin, Guangxi, China.; Laboratory of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China., Sun T; Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; Guangxi Health Commission Key Laboratory of Basic Research in Sphingolipid Metabolism Related Diseases, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; China-USA Lipids in Health and Disease Research Center, Guilin Medical University, 541001 Guilin, Guangxi, China.; Laboratory of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China., Wang Y; Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China., Dong W; Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China., Jin J; Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; Guangxi Health Commission Key Laboratory of Basic Research in Sphingolipid Metabolism Related Diseases, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; China-USA Lipids in Health and Disease Research Center, Guilin Medical University, 541001 Guilin, Guangxi, China.; Laboratory of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China., Pan Z; Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; Guangxi Health Commission Key Laboratory of Basic Research in Sphingolipid Metabolism Related Diseases, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; China-USA Lipids in Health and Disease Research Center, Guilin Medical University, 541001 Guilin, Guangxi, China.; Laboratory of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.
Source: Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2025 Dec 18; Vol. 30 (12), pp. 46946.
Publication Type: Journal Article
Journal Info: Publisher: IMR Press Country of Publication: Singapore NLM ID: 101612996 Publication Model: Print Cited Medium: Internet ISSN: 2768-6698 (Electronic) Linking ISSN: 27686698 NLM ISO Abbreviation: Front Biosci (Landmark Ed) Subsets: MEDLINE
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  Data: Hepatocyte-Derived Exosomes Reduce Hepatic Ischemia-Reperfusion (IR) Injury by Inhibiting Complement Activation.
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  Data: <searchLink fieldCode="AU" term="%22Yang+Z%22">Yang Z</searchLink>; Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; Guangxi Health Commission Key Laboratory of Basic Research in Sphingolipid Metabolism Related Diseases, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; China-USA Lipids in Health and Disease Research Center, Guilin Medical University, 541001 Guilin, Guangxi, China.; Laboratory of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Deng+B%22">Deng B</searchLink>; Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; Guangxi Health Commission Key Laboratory of Basic Research in Sphingolipid Metabolism Related Diseases, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; China-USA Lipids in Health and Disease Research Center, Guilin Medical University, 541001 Guilin, Guangxi, China.; Laboratory of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Sun+T%22">Sun T</searchLink>; Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; Guangxi Health Commission Key Laboratory of Basic Research in Sphingolipid Metabolism Related Diseases, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; China-USA Lipids in Health and Disease Research Center, Guilin Medical University, 541001 Guilin, Guangxi, China.; Laboratory of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Dong+W%22">Dong W</searchLink>; Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Jin+J%22">Jin J</searchLink>; Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; Guangxi Health Commission Key Laboratory of Basic Research in Sphingolipid Metabolism Related Diseases, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; China-USA Lipids in Health and Disease Research Center, Guilin Medical University, 541001 Guilin, Guangxi, China.; Laboratory of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Pan+Z%22">Pan Z</searchLink>; Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; Guangxi Health Commission Key Laboratory of Basic Research in Sphingolipid Metabolism Related Diseases, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.; China-USA Lipids in Health and Disease Research Center, Guilin Medical University, 541001 Guilin, Guangxi, China.; Laboratory of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Guilin Medical University, 541001 Guilin, Guangxi, China.
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      – TitleFull: Hepatocyte-Derived Exosomes Reduce Hepatic Ischemia-Reperfusion (IR) Injury by Inhibiting Complement Activation.
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              Text: 2025 Dec 18
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