Identifying early changes in imaging, plasma, and digital cognitive biomarkers that correspond to Alzheimer's disease pathology in the presence of autopsy-confirmed co-pathologies.

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Title: Identifying early changes in imaging, plasma, and digital cognitive biomarkers that correspond to Alzheimer's disease pathology in the presence of autopsy-confirmed co-pathologies.
Authors: Chen CD; Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, USA., Aguero C; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Melloni A; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Healy BC; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.; Biostatistics Center, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Thibault EG; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Fu JF; Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, USA., Farrell ME; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Schultz S; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Yang HS; Department of Neurology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, USA., Bellier JP; Department of Neurology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, USA., Chhatwal J; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Neurology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, USA., Webb PK; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Arnold S; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Penney D; Department of Neurology, Lahey Hospital and Medical Center, Burlington, Massachusetts, USA.; Department of Neurology, UMass Chan Medical School, Worcester, Massachusetts, USA.; Department of Neurology, Tufts University School of Medicine, Boston, Massachusetts, USA., Davis R; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Rentz D; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Neurology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, USA., Gomez-Isla T; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Sperling RA; Department of Neurology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, USA., Johnson KA; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Price JC; Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Jan; Vol. 22 (1), pp. e71092.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
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  Data: Identifying early changes in imaging, plasma, and digital cognitive biomarkers that correspond to Alzheimer's disease pathology in the presence of autopsy-confirmed co-pathologies.
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