TIGIT disruption rescues the antitumor activity of low avidity TCR-engineered T cells by increasing TCR signal strength. - Spiga M; Potenza A; Magnani Z; Beretta S; Camisa B; Conte L; Airaghi A; Mohammadi N; Perani L; Doglioni C; Ponzoni M; Sanvito F; et al. (Nature communications, 2026)