Epigenome-wide analysis identifies DNA methylation signatures associated with the infant pupillary light reflex, a candidate intermediate phenotype for autism.

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Title: Epigenome-wide analysis identifies DNA methylation signatures associated with the infant pupillary light reflex, a candidate intermediate phenotype for autism.
Authors: Fish LA; Department of Clinical, Educational and Health Psychology, University College London, London, UK.; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Gliga T; School of Psychology, University of East Anglia, Norwich, UK., Gui A; University of Rome Tor Vergata, Rome, Italy.; Department of Psychological Sciences, Birkbeck College, University of London, London, UK., Ali JB; Department of Psychological Sciences, Birkbeck College, University of London, London, UK., Mason L; Department of Psychological Sciences, Birkbeck College, University of London, London, UK., Johnson MH; Department of Psychological Sciences, Birkbeck College, University of London, London, UK.; Department of Psychology, Cambridge University, Cambridge, UK., Charman T; Department of Psychology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Falck-Ytter T; Development and Neurodiversity Lab, Department of Psychology, Uppsala University, Uppsala, Sweden.; Department of Women's and Children's Health, Center of Neurodevelopmental Disorders at Karolinska Institutet (KIND), Karolinska Institutet, Stockholm, Sweden., Jones EJH; Department of Psychological Sciences, Birkbeck College, University of London, London, UK.; Department of Child & Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom., Kandaswamy R; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Happé F; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Wong CCY; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK. Chloe.wong@kcl.ac.uk.; UK National Institute for Health and Care Research Biomedical Research Centre for Mental Health, South London and Maudsley Hospital, London, UK. Chloe.wong@kcl.ac.uk.
Source: Scientific reports [Sci Rep] 2026 Jan 08; Vol. 16 (1), pp. 325. Date of Electronic Publication: 2026 Jan 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Epigenome-wide analysis identifies DNA methylation signatures associated with the infant pupillary light reflex, a candidate intermediate phenotype for autism.
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  Data: <searchLink fieldCode="AU" term="%22Fish+LA%22">Fish LA</searchLink>; Department of Clinical, Educational and Health Psychology, University College London, London, UK.; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Gliga+T%22">Gliga T</searchLink>; School of Psychology, University of East Anglia, Norwich, UK.<br /><searchLink fieldCode="AU" term="%22Gui+A%22">Gui A</searchLink>; University of Rome Tor Vergata, Rome, Italy.; Department of Psychological Sciences, Birkbeck College, University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ali+JB%22">Ali JB</searchLink>; Department of Psychological Sciences, Birkbeck College, University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Mason+L%22">Mason L</searchLink>; Department of Psychological Sciences, Birkbeck College, University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Johnson+MH%22">Johnson MH</searchLink>; Department of Psychological Sciences, Birkbeck College, University of London, London, UK.; Department of Psychology, Cambridge University, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Charman+T%22">Charman T</searchLink>; Department of Psychology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Falck-Ytter+T%22">Falck-Ytter T</searchLink>; Development and Neurodiversity Lab, Department of Psychology, Uppsala University, Uppsala, Sweden.; Department of Women's and Children's Health, Center of Neurodevelopmental Disorders at Karolinska Institutet (KIND), Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Jones+EJH%22">Jones EJH</searchLink>; Department of Psychological Sciences, Birkbeck College, University of London, London, UK.; Department of Child & Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kandaswamy+R%22">Kandaswamy R</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Happé+F%22">Happé F</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Wong+CCY%22">Wong CCY</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK. Chloe.wong@kcl.ac.uk.; UK National Institute for Health and Care Research Biomedical Research Centre for Mental Health, South London and Maudsley Hospital, London, UK. Chloe.wong@kcl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Jan 08; Vol. 16 (1), pp. 325. <i>Date of Electronic Publication: </i>2026 Jan 08.
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