Mapping the secondary response to traumatic brain injury using spatial transcriptomics shows acute 4-aminopyridine treatment mitigates axonal and molecular pathology.
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| Title: | Mapping the secondary response to traumatic brain injury using spatial transcriptomics shows acute 4-aminopyridine treatment mitigates axonal and molecular pathology. |
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| Authors: | Sullivan GM; Department of Anatomy, Physiology and Genetics in the School of Medicine at the Uniformed Services University of the Health Sciences, Bethesda, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA.; Military Traumatic Brain Injury Initiative (MTBI2), Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, MD, USA., Radomski KL; Department of Anatomy, Physiology and Genetics in the School of Medicine at the Uniformed Services University of the Health Sciences, Bethesda, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA., He S; Department of Anatomy, Physiology and Genetics in the School of Medicine at the Uniformed Services University of the Health Sciences, Bethesda, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA.; Center for Military Precision Health, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, MD, USA., Wilkerson MD; Department of Anatomy, Physiology and Genetics in the School of Medicine at the Uniformed Services University of the Health Sciences, Bethesda, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA.; Center for Military Precision Health, Bethesda, MD, USA., Dalgard CL; Department of Anatomy, Physiology and Genetics in the School of Medicine at the Uniformed Services University of the Health Sciences, Bethesda, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA.; Center for Military Precision Health, Bethesda, MD, USA., Alba C; Department of Anatomy, Physiology and Genetics in the School of Medicine at the Uniformed Services University of the Health Sciences, Bethesda, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA.; Center for Military Precision Health, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, MD, USA., Zi X; Department of Anatomy, Physiology and Genetics in the School of Medicine at the Uniformed Services University of the Health Sciences, Bethesda, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA.; Military Traumatic Brain Injury Initiative (MTBI2), Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, MD, USA., Doughty ML; Department of Anatomy, Physiology and Genetics in the School of Medicine at the Uniformed Services University of the Health Sciences, Bethesda, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA., Armstrong RC; Department of Anatomy, Physiology and Genetics in the School of Medicine at the Uniformed Services University of the Health Sciences, Bethesda, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA. regina.armstrong@usuhs.edu.; Military Traumatic Brain Injury Initiative (MTBI2), Bethesda, MD, USA. regina.armstrong@usuhs.edu. |
| Source: | Acta neuropathologica communications [Acta Neuropathol Commun] 2026 Jan 08; Vol. 14 (1), pp. 36. Date of Electronic Publication: 2026 Jan 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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