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Central hypocretin/orexin administration alleviates sleep/wake disturbances, anhedonia, and neuroinflammation in an animal model of seasonal affective disorder.

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Title: Central hypocretin/orexin administration alleviates sleep/wake disturbances, anhedonia, and neuroinflammation in an animal model of seasonal affective disorder.
Authors: Costello A; Department of Psychology, Behavioral Neuroscience Program, East Lansing, MI, USA., Linning-Duffy K; Department of Psychology, Behavioral Neuroscience Program, East Lansing, MI, USA., Shi J; Department of Psychology, Behavioral Neuroscience Program, East Lansing, MI, USA., Lonstein JS; Department of Psychology, Behavioral Neuroscience Program, East Lansing, MI, USA.; Neuroscience Program, Michigan State University, East Lansing, MI, USA., Yan L; Department of Psychology, Behavioral Neuroscience Program, East Lansing, MI, USA.; Neuroscience Program, Michigan State University, East Lansing, MI, USA.
Source: Annals of medicine [Ann Med] 2026 Dec; Vol. 58 (1), pp. 2611202. Date of Electronic Publication: 2026 Jan 08.
Publication Type: Journal Article
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Central hypocretin/orexin administration alleviates sleep/wake disturbances, anhedonia, and neuroinflammation in an animal model of seasonal affective disorder.
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  Data: <searchLink fieldCode="AU" term="%22Costello+A%22">Costello A</searchLink>; Department of Psychology, Behavioral Neuroscience Program, East Lansing, MI, USA.<br /><searchLink fieldCode="AU" term="%22Linning-Duffy+K%22">Linning-Duffy K</searchLink>; Department of Psychology, Behavioral Neuroscience Program, East Lansing, MI, USA.<br /><searchLink fieldCode="AU" term="%22Shi+J%22">Shi J</searchLink>; Department of Psychology, Behavioral Neuroscience Program, East Lansing, MI, USA.<br /><searchLink fieldCode="AU" term="%22Lonstein+JS%22">Lonstein JS</searchLink>; Department of Psychology, Behavioral Neuroscience Program, East Lansing, MI, USA.; Neuroscience Program, Michigan State University, East Lansing, MI, USA.<br /><searchLink fieldCode="AU" term="%22Yan+L%22">Yan L</searchLink>; Department of Psychology, Behavioral Neuroscience Program, East Lansing, MI, USA.; Neuroscience Program, Michigan State University, East Lansing, MI, USA.
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  Data: <searchLink fieldCode="JN" term="%228906388%22">Annals of medicine</searchLink> [Ann Med] 2026 Dec; Vol. 58 (1), pp. 2611202. <i>Date of Electronic Publication: </i>2026 Jan 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Informa+Healthcare%22">Informa Healthcare </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8906388 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1365-2060 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207853890%22">07853890 </searchLink><i>NLM ISO Abbreviation: </i>Ann Med <i>Subsets: </i>MEDLINE
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        Value: 10.1080/07853890.2025.2611202
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      – Code: eng
        Text: English
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              Text: 2026 Dec
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