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Structural, biophysical, and virological mechanistic characterization of HIV-1 capsid-targeting antivirals.

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Title: Structural, biophysical, and virological mechanistic characterization of HIV-1 capsid-targeting antivirals.
Authors: Kirby KA; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA., McFadden WM; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA., Wang L; Center for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN., Du H; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA., Zhang H; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA., Castaner AE; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA., Lorson ZC; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA., Nafisi A; Institute of Molecular Biophysics and Department of Biological Sciences, Florida State University, Tallahassee, FL., Luchsinger C; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY., Hachiya A; Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Aichi, Japan., Cilento ME; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA., Snyder AA; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA., Ravichandran SM; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA., Cai X; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA., Tedbury PR; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA., Francis AC; Institute of Molecular Biophysics and Department of Biological Sciences, Florida State University, Tallahassee, FL., Melikyan GB; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA., Diaz-Griffero F; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY., Wang Z; Center for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN., Sarafianos SG; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 31. Date of Electronic Publication: 2025 Dec 31.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Structural, biophysical, and virological mechanistic characterization of HIV-1 capsid-targeting antivirals.
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  Data: <searchLink fieldCode="AU" term="%22Kirby+KA%22">Kirby KA</searchLink>; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22McFadden+WM%22">McFadden WM</searchLink>; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Center for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN.<br /><searchLink fieldCode="AU" term="%22Du+H%22">Du H</searchLink>; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Castaner+AE%22">Castaner AE</searchLink>; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Lorson+ZC%22">Lorson ZC</searchLink>; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Nafisi+A%22">Nafisi A</searchLink>; Institute of Molecular Biophysics and Department of Biological Sciences, Florida State University, Tallahassee, FL.<br /><searchLink fieldCode="AU" term="%22Luchsinger+C%22">Luchsinger C</searchLink>; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY.<br /><searchLink fieldCode="AU" term="%22Hachiya+A%22">Hachiya A</searchLink>; Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Cilento+ME%22">Cilento ME</searchLink>; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Snyder+AA%22">Snyder AA</searchLink>; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Ravichandran+SM%22">Ravichandran SM</searchLink>; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Cai+X%22">Cai X</searchLink>; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Tedbury+PR%22">Tedbury PR</searchLink>; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Francis+AC%22">Francis AC</searchLink>; Institute of Molecular Biophysics and Department of Biological Sciences, Florida State University, Tallahassee, FL.<br /><searchLink fieldCode="AU" term="%22Melikyan+GB%22">Melikyan GB</searchLink>; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Diaz-Griffero+F%22">Diaz-Griffero F</searchLink>; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Center for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN.<br /><searchLink fieldCode="AU" term="%22Sarafianos+SG%22">Sarafianos SG</searchLink>; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Dec 31. <i>Date of Electronic Publication: </i>2025 Dec 31.
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