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Viral control is required for intravenous BCG-mediated protection against tuberculosis in simian immunodeficiency virus-infected macaques.

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Title: Viral control is required for intravenous BCG-mediated protection against tuberculosis in simian immunodeficiency virus-infected macaques.
Authors: Jauro S; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA., Larson EC; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA., Wahlberg B; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA., Chao MC; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Rodgers MA; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA., Gleim JL; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA., Hood LE; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA., Sunny PS; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA., Collins MK; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA., Tomko JA; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA., Borish HJ; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA., Malin MA; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA., Maiello P; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA., Demarco T; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA., Fortune SM; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lin PL; Center for Vaccine Research, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.; Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA., Flynn JL; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA., Scanga CA; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.
Source: Research square [Res Sq] 2025 Dec 10. Date of Electronic Publication: 2025 Dec 10.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Viral control is required for intravenous BCG-mediated protection against tuberculosis in simian immunodeficiency virus-infected macaques.
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  Data: <searchLink fieldCode="AU" term="%22Jauro+S%22">Jauro S</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Larson+EC%22">Larson EC</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Wahlberg+B%22">Wahlberg B</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Chao+MC%22">Chao MC</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rodgers+MA%22">Rodgers MA</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Gleim+JL%22">Gleim JL</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Hood+LE%22">Hood LE</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Sunny+PS%22">Sunny PS</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Collins+MK%22">Collins MK</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Tomko+JA%22">Tomko JA</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Borish+HJ%22">Borish HJ</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Malin+MA%22">Malin MA</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Maiello+P%22">Maiello P</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Demarco+T%22">Demarco T</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Fortune+SM%22">Fortune SM</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lin+PL%22">Lin PL</searchLink>; Center for Vaccine Research, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.; Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Flynn+JL%22">Flynn JL</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Scanga+CA%22">Scanga CA</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.
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        Value: 10.21203/rs.3.rs-8225191/v1
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        Text: English
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      – TitleFull: Viral control is required for intravenous BCG-mediated protection against tuberculosis in simian immunodeficiency virus-infected macaques.
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              Text: 2025 Dec 10
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