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Three Versus 6 Months of Adjuvant Oxaliplatin-Fluoropyrimidine Chemotherapy for Colorectal Cancer: Final Results of SCOT-An International, Randomized, Phase III, Noninferiority Trial.

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Title: Three Versus 6 Months of Adjuvant Oxaliplatin-Fluoropyrimidine Chemotherapy for Colorectal Cancer: Final Results of SCOT-An International, Randomized, Phase III, Noninferiority Trial.
Authors: Iveson T; University of Southampton, Southampton, United Kingdom., Saunders MP; The Christie Hospital, Manchester, United Kingdom., Kelly C; Glasgow Oncology Clinical Trials Unit, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Kerr RS; Department of Oncology, University of Oxford, Oxford, United Kingdom., Cassidy J; Glasgow Oncology Clinical Trials Unit, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Hollander NH; Department of Oncology and Palliative Care, Zealand University Hospital, Naestved, Denmark., Tabernero J; Vall d'Hebron Hospital Campus and Institute of Oncology (VHIO), UVic-UCC, IOB-Quiron, CIBERONC, Barcelona, Spain., Haydon A; Australasian Gastro-Intestinal Trials Group (AGITG), Alfred Hospital, Melbourne, Australia., Glimelius B; Department of Immunology, Genetics and Pathology, University of Uppsala, Uppsala, Sweden., Harkin A; Glasgow Oncology Clinical Trials Unit, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Allan K; Glasgow Oncology Clinical Trials Unit, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., McQueen J; Glasgow Oncology Clinical Trials Unit, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Pearson S; OCTO, Department of Oncology, University of Oxford, Oxford, United Kingdom., Boyd KA; Institute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom., Briggs AH; Institute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom., Waterston A; Beatson West of Scotland Cancer Centre, NHS GGC HB, Glasgow, United Kingdom., Medley L; Royal United Hospital, Bath, United Kingdom., Ellis R; Royal Cornwall Hospitals NHS Trust, Cornwall, United Kingdom., Dhadda AS; Castle Hill Hospital, Hull, United Kingdom., Harrison M; Mount Vernon Cancer Centre, Northwood, United Kingdom., Falk S; Bristol Cancer Institute, Bristol, United Kingdom., Rees C; Southampton University Hospital NHS Foundation Trust, Southampton, United Kingdom., Olesen RK; Department of Oncology, Aarhus University Hospital, Aarhus C, Denmark., Propper D; Barts Cancer Institute, Queen Mary, University of London, London, United Kingdom., Bridgewater J; University College London, London, United Kingdom (part funded by the UCLH/UCL Biomedical Research Centre)., Azzabi A; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom., Cunningham D; Royal Marsden, London, United Kingdom (funded by NIHR BRC at the Royal Marsden)., Hickish T; University Hospitals Dorset/Bournemouth University, Bournemouth, United Kingdom., Gollins S; North Wales Cancer Treatment Centre, Rhyl, United Kingdom., Wasan HS; Hammersmith Hospital, Imperial College London, London, United Kingdom., Church D; Department of Oncology, University of Oxford, Oxford, United Kingdom., Domingo E; Department of Oncology, University of Oxford, Oxford, United Kingdom.
Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2026 Mar; Vol. 44 (7), pp. 534-539. Date of Electronic Publication: 2026 Jan 09.
Publication Type: Journal Article
Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE; In Process
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  Data: Three Versus 6 Months of Adjuvant Oxaliplatin-Fluoropyrimidine Chemotherapy for Colorectal Cancer: Final Results of SCOT-An International, Randomized, Phase III, Noninferiority Trial.
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Vall d'Hebron Hospital Campus and Institute of Oncology (VHIO), UVic-UCC, IOB-Quiron, CIBERONC, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Haydon+A%22">Haydon A</searchLink>; Australasian Gastro-Intestinal Trials Group (AGITG), Alfred Hospital, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Glimelius+B%22">Glimelius B</searchLink>; Department of Immunology, Genetics and Pathology, University of Uppsala, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Harkin+A%22">Harkin A</searchLink>; Glasgow Oncology Clinical Trials Unit, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Allan+K%22">Allan K</searchLink>; Glasgow Oncology Clinical Trials Unit, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22McQueen+J%22">McQueen J</searchLink>; Glasgow Oncology Clinical Trials Unit, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pearson+S%22">Pearson S</searchLink>; OCTO, Department of Oncology, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Boyd+KA%22">Boyd KA</searchLink>; Institute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Briggs+AH%22">Briggs AH</searchLink>; Institute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Waterston+A%22">Waterston A</searchLink>; Beatson West of Scotland Cancer Centre, NHS GGC HB, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Medley+L%22">Medley L</searchLink>; Royal United Hospital, Bath, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ellis+R%22">Ellis R</searchLink>; Royal Cornwall Hospitals NHS Trust, Cornwall, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dhadda+AS%22">Dhadda AS</searchLink>; Castle Hill Hospital, Hull, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Harrison+M%22">Harrison M</searchLink>; Mount Vernon Cancer Centre, Northwood, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Falk+S%22">Falk S</searchLink>; Bristol Cancer Institute, Bristol, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rees+C%22">Rees C</searchLink>; Southampton University Hospital NHS Foundation Trust, Southampton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Olesen+RK%22">Olesen RK</searchLink>; Department of Oncology, Aarhus University Hospital, Aarhus C, Denmark.<br /><searchLink fieldCode="AU" term="%22Propper+D%22">Propper D</searchLink>; Barts Cancer Institute, Queen Mary, University of London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Bridgewater+J%22">Bridgewater J</searchLink>; University College London, London, United Kingdom (part funded by the UCLH/UCL Biomedical Research Centre).<br /><searchLink fieldCode="AU" term="%22Azzabi+A%22">Azzabi A</searchLink>; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cunningham+D%22">Cunningham D</searchLink>; Royal Marsden, London, United Kingdom (funded by NIHR BRC at the Royal Marsden).<br /><searchLink fieldCode="AU" term="%22Hickish+T%22">Hickish T</searchLink>; University Hospitals Dorset/Bournemouth University, Bournemouth, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gollins+S%22">Gollins S</searchLink>; North Wales Cancer Treatment Centre, Rhyl, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Wasan+HS%22">Wasan HS</searchLink>; Hammersmith Hospital, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Church+D%22">Church D</searchLink>; Department of Oncology, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Domingo+E%22">Domingo E</searchLink>; Department of Oncology, University of Oxford, Oxford, United Kingdom.
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  Data: <searchLink fieldCode="JN" term="%228309333%22">Journal of clinical oncology : official journal of the American Society of Clinical Oncology</searchLink> [J Clin Oncol] 2026 Mar; Vol. 44 (7), pp. 534-539. <i>Date of Electronic Publication: </i>2026 Jan 09.
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