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Two-year persistence of MERS-CoV-specific antibody and T cell responses after MVA-MERS-S vaccination in healthy adults.

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Title: Two-year persistence of MERS-CoV-specific antibody and T cell responses after MVA-MERS-S vaccination in healthy adults.
Authors: Mayer L; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany. l.mayer@uke.de.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany. l.mayer@uke.de.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany. l.mayer@uke.de., Fathi A; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.; First Department of Medicine, Division of Infectious Diseases, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Weichel HM; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany., Raadsen MP; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands., Dahlke C; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany., Mykytyn A; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands., Rodon J; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany., Gerresheim GK; Institute of Virology, Philipps University Marburg, Marburg, Germany.; German Center for Infection Research, partner site Gießen-Marburg-Langen, Marburg, Germany., Te Marvelde MR; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands., Weskamm LM; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany., Grewe I; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany., Schlesner C; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany., Lütgehetmann M; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Drosten C; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; German Center for Infection Research, associated partner Charité, Berlin, Germany., Becker S; Institute of Virology, Philipps University Marburg, Marburg, Germany.; German Center for Infection Research, partner site Gießen-Marburg-Langen, Marburg, Germany., Haagmans BL; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands., Hardtke S; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany., Addo MM; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany. m.addo@uke.de.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany. m.addo@uke.de.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany. m.addo@uke.de.
Source: Nature communications [Nat Commun] 2026 Jan 09; Vol. 17 (1), pp. 480. Date of Electronic Publication: 2026 Jan 09.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Two-year persistence of MERS-CoV-specific antibody and T cell responses after MVA-MERS-S vaccination in healthy adults.
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  Data: <searchLink fieldCode="AU" term="%22Mayer+L%22">Mayer L</searchLink>; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany. l.mayer@uke.de.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany. l.mayer@uke.de.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany. l.mayer@uke.de.<br /><searchLink fieldCode="AU" term="%22Fathi+A%22">Fathi A</searchLink>; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.; First Department of Medicine, Division of Infectious Diseases, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Weichel+HM%22">Weichel HM</searchLink>; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Raadsen+MP%22">Raadsen MP</searchLink>; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dahlke+C%22">Dahlke C</searchLink>; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Mykytyn+A%22">Mykytyn A</searchLink>; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rodon+J%22">Rodon J</searchLink>; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Gerresheim+GK%22">Gerresheim GK</searchLink>; Institute of Virology, Philipps University Marburg, Marburg, Germany.; German Center for Infection Research, partner site Gießen-Marburg-Langen, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Te+Marvelde+MR%22">Te Marvelde MR</searchLink>; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Weskamm+LM%22">Weskamm LM</searchLink>; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Grewe+I%22">Grewe I</searchLink>; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schlesner+C%22">Schlesner C</searchLink>; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lütgehetmann+M%22">Lütgehetmann M</searchLink>; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Drosten+C%22">Drosten C</searchLink>; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; German Center for Infection Research, associated partner Charité, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Becker+S%22">Becker S</searchLink>; Institute of Virology, Philipps University Marburg, Marburg, Germany.; German Center for Infection Research, partner site Gießen-Marburg-Langen, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Haagmans+BL%22">Haagmans BL</searchLink>; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hardtke+S%22">Hardtke S</searchLink>; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Addo+MM%22">Addo MM</searchLink>; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany. m.addo@uke.de.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany. m.addo@uke.de.; German Center for Infection Research, partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany. m.addo@uke.de.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Jan 09; Vol. 17 (1), pp. 480. <i>Date of Electronic Publication: </i>2026 Jan 09.
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