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Distinct genetic profiles of obesity have different effects on breast cancer risk: leveraging Mendelian randomisation to interrogate causal pathways and identify mediating proteins.

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Title: Distinct genetic profiles of obesity have different effects on breast cancer risk: leveraging Mendelian randomisation to interrogate causal pathways and identify mediating proteins.
Authors: Marchal MI; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 751 85, Uppsala, Sweden., Mutie PM; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 751 85, Uppsala, Sweden., Azimi T; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 751 85, Uppsala, Sweden., Deng YA; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 751 85, Uppsala, Sweden., Karlsson T; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 751 85, Uppsala, Sweden., Johansson Å; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 751 85, Uppsala, Sweden. asa.johansson@igp.uu.se.
Source: Breast cancer research : BCR [Breast Cancer Res] 2026 Jan 09; Vol. 28 (1), pp. 23. Date of Electronic Publication: 2026 Jan 09.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Distinct genetic profiles of obesity have different effects on breast cancer risk: leveraging Mendelian randomisation to interrogate causal pathways and identify mediating proteins.
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  Data: <searchLink fieldCode="AU" term="%22Marchal+MI%22">Marchal MI</searchLink>; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 751 85, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Mutie+PM%22">Mutie PM</searchLink>; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 751 85, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Azimi+T%22">Azimi T</searchLink>; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 751 85, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Deng+YA%22">Deng YA</searchLink>; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 751 85, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Karlsson+T%22">Karlsson T</searchLink>; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 751 85, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Johansson+Å%22">Johansson Å</searchLink>; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 751 85, Uppsala, Sweden. asa.johansson@igp.uu.se.
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  Data: <searchLink fieldCode="JN" term="%22100927353%22">Breast cancer research : BCR</searchLink> [Breast Cancer Res] 2026 Jan 09; Vol. 28 (1), pp. 23. <i>Date of Electronic Publication: </i>2026 Jan 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central+Ltd%22">BioMed Central Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100927353 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1465-542X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214655411%22">14655411 </searchLink><i>NLM ISO Abbreviation: </i>Breast Cancer Res <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13058-025-02214-3
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      – Code: eng
        Text: English
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      – TitleFull: Distinct genetic profiles of obesity have different effects on breast cancer risk: leveraging Mendelian randomisation to interrogate causal pathways and identify mediating proteins.
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              Text: 2026 Jan 09
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              Value: 28
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