Caloric Restriction Enhances Chemotherapy Efficacy and Reshapes Stress Responses in Sarcoma.

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Title: Caloric Restriction Enhances Chemotherapy Efficacy and Reshapes Stress Responses in Sarcoma.
Authors: Martins JA; Metabolic Diseases, Exercise and Nutrition Group (DOMEN), Glauto Tuquarre Metabolic Diseases Laboratory (LabGT), Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Pereira IC; Metabolic Diseases, Exercise and Nutrition Group (DOMEN), Glauto Tuquarre Metabolic Diseases Laboratory (LabGT), Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Reinaldo TS; Metabolic Diseases, Exercise and Nutrition Group (DOMEN), Glauto Tuquarre Metabolic Diseases Laboratory (LabGT), Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Sousa DJM; Metabolic Diseases, Exercise and Nutrition Group (DOMEN), Glauto Tuquarre Metabolic Diseases Laboratory (LabGT), Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Rodrigues IV; Metabolic Diseases, Exercise and Nutrition Group (DOMEN), Glauto Tuquarre Metabolic Diseases Laboratory (LabGT), Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Rego BMP; Metabolic Diseases, Exercise and Nutrition Group (DOMEN), Glauto Tuquarre Metabolic Diseases Laboratory (LabGT), Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Oliveira AM; Metabolic Diseases, Exercise and Nutrition Group (DOMEN), Glauto Tuquarre Metabolic Diseases Laboratory (LabGT), Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Nobre TA; Toxicological Genetics Research Laboratory (LAPGENIC), Department of Biochemistry and Pharmacology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Sousa AA; Toxicological Genetics Research Laboratory (LAPGENIC), Department of Biochemistry and Pharmacology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Lago JPADD; Toxicological Genetics Research Laboratory (LAPGENIC), Department of Biochemistry and Pharmacology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Sousa RWR; Laboratory of Experimental Cancerology (LABCANCER), Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Menezes DP; Laboratory of Antineoplastic Pharmacology (LAFAN), Department of Biochemistry and Pharmacology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Silva ACAD; Metabolic Diseases, Exercise and Nutrition Group (DOMEN), Glauto Tuquarre Metabolic Diseases Laboratory (LabGT), Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Dittz D; Laboratory of Antineoplastic Pharmacology (LAFAN), Department of Biochemistry and Pharmacology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Nunes AMV; Pathology and Histology Laboratory (LaPaH), Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Silva VC; Genomic Surveillance and Molecular Biology Laboratory, Oswaldo Cruz Foundation, Teresina 64049-550, PI, Brazil., Severo JS; Metabolic Diseases, Exercise and Nutrition Group (DOMEN), Glauto Tuquarre Metabolic Diseases Laboratory (LabGT), Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Silva MTBD; Laboratory of Physiology, Center for Drug Discovery and Innovative Medicines (MedInUP/RISE-Health): Health Research Network, Department of Immuno-Physiology and Pharmacology, School of Medicine and Biomedical Science, University of Porto, 4099-002 Porto, Portugal., Ferreira PMP; Laboratory of Experimental Cancerology (LABCANCER), Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., E Sousa JMC; Toxicological Genetics Research Laboratory (LAPGENIC), Department of Biochemistry and Pharmacology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Torres-Leal FL; Metabolic Diseases, Exercise and Nutrition Group (DOMEN), Glauto Tuquarre Metabolic Diseases Laboratory (LabGT), Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil.
Source: Cancers [Cancers (Basel)] 2025 Dec 29; Vol. 18 (1). Date of Electronic Publication: 2025 Dec 29.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2072-6694
DOI:10.3390/cancers18010110