View in EDS

Ex vivo drug sensitivity profiling to complement molecular profiling in pediatric precision oncology.

Saved in:
Bibliographic Details
Title: Ex vivo drug sensitivity profiling to complement molecular profiling in pediatric precision oncology.
Authors: Schoonbeek MC; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Gestraud P; INSERM U1331 Computational Oncology, Institut Curie, PSL Research University, Mines Paris Tech, Paris, France., Vernooij L; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Boltjes A; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Amo-Addae V; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., van Luik M; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Del Nery E; BioPhenics High-Content Screening Laboratory, Department of Translational Research, Curie Institute, Paris, France., Bellini A; RTOP (Translational Research in Pediatric Oncology), U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, PSL University, Curie Institute, Paris, France., Chua E; INSERM U1331 Computational Oncology, Institut Curie, PSL Research University, Mines Paris Tech, Paris, France., Swaak S; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Looze EJ; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Pietiäinen VM; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki FI, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland., Turunen LL; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki FI, Helsinki, Finland., Saarela JS; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki FI, Helsinki, Finland., Schueler J; Charles River Laboratories Germany GmbH, Freiburg, Germany., Indersie E; Xentech, Evry, France., Gürgen D; Experimental Pharmacology and Oncology Berlin-Buch GmbH, Berlin, Germany., Scotlandi K; IRCCS Istituto Ortopedico Rizzoli, Experimental Oncology Laboratory, Bologna, Italy., Eggert A; Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany., Bouarich-Bourimi R; RTOP (Translational Research in Pediatric Oncology), U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, PSL University, Curie Institute, Paris, France., Bourdeaut F; Paris Cité University, Paris, France, U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, Curie Institute, Paris, France., Zaidi S; RTOP (Translational Research in Pediatric Oncology), U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, PSL University, Curie Institute, Paris, France., Surdez D; Balgrist University Hospital, Faculty of Medicine, University of Zurich (UZH), Zurich, Switzerland., Carcaboso ÁM; SJD Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu, Sant Joan de Déu Barcelona Hospital, Institut de Recerca Sant Joan de Deu (IRSJD), Barcelona, Spain., Geoerger B; Gustave Roussy Cancer Campus, Villejuif, France., Federico A; Hopp Children's Cancer Center (KiTZ), DKFZ and German Cancer Consortium (DKTK), Heidelberg, Germany.; TRON-Translational Oncology at the University Medical Centre of the Johannes Gutenberg University, Mainz, Germany., Kool M; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Hopp Children's Cancer Center (KiTZ), DKFZ and German Cancer Consortium (DKTK), Heidelberg, Germany.; Utrecht University Medical Center, Utrecht University, Utrecht, The Netherlands., Iddir Y; RTOP (Translational Research in Pediatric Oncology), U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, PSL University, Curie Institute, Paris, France., Saint-Charles A; RTOP (Translational Research in Pediatric Oncology), U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, PSL University, Curie Institute, Paris, France., Saberi-Ansari E; RTOP (Translational Research in Pediatric Oncology), U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, PSL University, Curie Institute, Paris, France., Cavalli F; INSERM U1331 Computational Oncology, Institut Curie, PSL Research University, Mines Paris Tech, Paris, France., Gopisetty A; Hopp Children's Cancer Center (KiTZ), DKFZ and German Cancer Consortium (DKTK), Heidelberg, Germany.; ITCC-P4 gGmbH, Heidelberg, Germany., Rief EM; ITCC-P4 gGmbH, Heidelberg, Germany., Caron HN; Hoffman-La Roche, Basel, Switzerland., Stancato L; ITCC-P4 gGmbH, Heidelberg, Germany.; Indiana Biosciences Research Institute, Indianapolis, IN, USA., Vassal G; Gustave Roussy Cancer Campus, Villejuif, France.; ITCC-P4 gGmbH, Heidelberg, Germany., Pfister S; Hopp Children's Cancer Center (KiTZ), DKFZ and German Cancer Consortium (DKTK), Heidelberg, Germany.; ITCC-P4 gGmbH, Heidelberg, Germany., Koster J; Amsterdam UMC, R2 Platform, Amsterdam, The Netherlands., Eising S; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., van Hooff SR; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Amsterdam UMC, Amsterdam, The Netherlands., van den Boogaard ML; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Schleiermacher G; RTOP (Translational Research in Pediatric Oncology), U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, PSL University, Curie Institute, Paris, France., Molenaar JJ; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands. j.j.molenaar@prinsesmaximacentrum.nl.; Utrecht University, Department of Pharmaceutical Sciences, Utrecht, The Netherlands. j.j.molenaar@prinsesmaximacentrum.nl.
Source: NPJ precision oncology [NPJ Precis Oncol] 2026 Jan 10; Vol. 10 (1). Date of Electronic Publication: 2026 Jan 10.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41520034
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Ex vivo drug sensitivity profiling to complement molecular profiling in pediatric precision oncology.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Schoonbeek+MC%22">Schoonbeek MC</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gestraud+P%22">Gestraud P</searchLink>; INSERM U1331 Computational Oncology, Institut Curie, PSL Research University, Mines Paris Tech, Paris, France.<br /><searchLink fieldCode="AU" term="%22Vernooij+L%22">Vernooij L</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Boltjes+A%22">Boltjes A</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Amo-Addae+V%22">Amo-Addae V</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Luik+M%22">van Luik M</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Del+Nery+E%22">Del Nery E</searchLink>; BioPhenics High-Content Screening Laboratory, Department of Translational Research, Curie Institute, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bellini+A%22">Bellini A</searchLink>; RTOP (Translational Research in Pediatric Oncology), U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, PSL University, Curie Institute, Paris, France.<br /><searchLink fieldCode="AU" term="%22Chua+E%22">Chua E</searchLink>; INSERM U1331 Computational Oncology, Institut Curie, PSL Research University, Mines Paris Tech, Paris, France.<br /><searchLink fieldCode="AU" term="%22Swaak+S%22">Swaak S</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Looze+EJ%22">Looze EJ</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pietiäinen+VM%22">Pietiäinen VM</searchLink>; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki FI, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Turunen+LL%22">Turunen LL</searchLink>; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki FI, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Saarela+JS%22">Saarela JS</searchLink>; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki FI, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Schueler+J%22">Schueler J</searchLink>; Charles River Laboratories Germany GmbH, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Indersie+E%22">Indersie E</searchLink>; Xentech, Evry, France.<br /><searchLink fieldCode="AU" term="%22Gürgen+D%22">Gürgen D</searchLink>; Experimental Pharmacology and Oncology Berlin-Buch GmbH, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Scotlandi+K%22">Scotlandi K</searchLink>; IRCCS Istituto Ortopedico Rizzoli, Experimental Oncology Laboratory, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Eggert+A%22">Eggert A</searchLink>; Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Bouarich-Bourimi+R%22">Bouarich-Bourimi R</searchLink>; RTOP (Translational Research in Pediatric Oncology), U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, PSL University, Curie Institute, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bourdeaut+F%22">Bourdeaut F</searchLink>; Paris Cité University, Paris, France, U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, Curie Institute, Paris, France.<br /><searchLink fieldCode="AU" term="%22Zaidi+S%22">Zaidi S</searchLink>; RTOP (Translational Research in Pediatric Oncology), U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, PSL University, Curie Institute, Paris, France.<br /><searchLink fieldCode="AU" term="%22Surdez+D%22">Surdez D</searchLink>; Balgrist University Hospital, Faculty of Medicine, University of Zurich (UZH), Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Carcaboso+ÁM%22">Carcaboso ÁM</searchLink>; SJD Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu, Sant Joan de Déu Barcelona Hospital, Institut de Recerca Sant Joan de Deu (IRSJD), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Geoerger+B%22">Geoerger B</searchLink>; Gustave Roussy Cancer Campus, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Federico+A%22">Federico A</searchLink>; Hopp Children's Cancer Center (KiTZ), DKFZ and German Cancer Consortium (DKTK), Heidelberg, Germany.; TRON-Translational Oncology at the University Medical Centre of the Johannes Gutenberg University, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Kool+M%22">Kool M</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Hopp Children's Cancer Center (KiTZ), DKFZ and German Cancer Consortium (DKTK), Heidelberg, Germany.; Utrecht University Medical Center, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Iddir+Y%22">Iddir Y</searchLink>; RTOP (Translational Research in Pediatric Oncology), U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, PSL University, Curie Institute, Paris, France.<br /><searchLink fieldCode="AU" term="%22Saint-Charles+A%22">Saint-Charles A</searchLink>; RTOP (Translational Research in Pediatric Oncology), U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, PSL University, Curie Institute, Paris, France.<br /><searchLink fieldCode="AU" term="%22Saberi-Ansari+E%22">Saberi-Ansari E</searchLink>; RTOP (Translational Research in Pediatric Oncology), U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, PSL University, Curie Institute, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cavalli+F%22">Cavalli F</searchLink>; INSERM U1331 Computational Oncology, Institut Curie, PSL Research University, Mines Paris Tech, Paris, France.<br /><searchLink fieldCode="AU" term="%22Gopisetty+A%22">Gopisetty A</searchLink>; Hopp Children's Cancer Center (KiTZ), DKFZ and German Cancer Consortium (DKTK), Heidelberg, Germany.; ITCC-P4 gGmbH, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Rief+EM%22">Rief EM</searchLink>; ITCC-P4 gGmbH, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Caron+HN%22">Caron HN</searchLink>; Hoffman-La Roche, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Stancato+L%22">Stancato L</searchLink>; ITCC-P4 gGmbH, Heidelberg, Germany.; Indiana Biosciences Research Institute, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Vassal+G%22">Vassal G</searchLink>; Gustave Roussy Cancer Campus, Villejuif, France.; ITCC-P4 gGmbH, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Pfister+S%22">Pfister S</searchLink>; Hopp Children's Cancer Center (KiTZ), DKFZ and German Cancer Consortium (DKTK), Heidelberg, Germany.; ITCC-P4 gGmbH, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Koster+J%22">Koster J</searchLink>; Amsterdam UMC, R2 Platform, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Eising+S%22">Eising S</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Hooff+SR%22">van Hooff SR</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Amsterdam UMC, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Boogaard+ML%22">van den Boogaard ML</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Schleiermacher+G%22">Schleiermacher G</searchLink>; RTOP (Translational Research in Pediatric Oncology), U1330 INSERM, SIREDO Integrated Pediatric Oncology Center, PSL University, Curie Institute, Paris, France.<br /><searchLink fieldCode="AU" term="%22Molenaar+JJ%22">Molenaar JJ</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands. j.j.molenaar@prinsesmaximacentrum.nl.; Utrecht University, Department of Pharmaceutical Sciences, Utrecht, The Netherlands. j.j.molenaar@prinsesmaximacentrum.nl.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101708166%22">NPJ precision oncology</searchLink> [NPJ Precis Oncol] 2026 Jan 10; Vol. 10 (1). <i>Date of Electronic Publication: </i>2026 Jan 10.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101708166 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2397-768X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222397768X%22">2397768X </searchLink><i>NLM ISO Abbreviation: </i>NPJ Precis Oncol <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41520034
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41698-025-01266-0
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Ex vivo drug sensitivity profiling to complement molecular profiling in pediatric precision oncology.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Schoonbeek MC
      – PersonEntity:
          Name:
            NameFull: Gestraud P
      – PersonEntity:
          Name:
            NameFull: Vernooij L
      – PersonEntity:
          Name:
            NameFull: Boltjes A
      – PersonEntity:
          Name:
            NameFull: Amo-Addae V
      – PersonEntity:
          Name:
            NameFull: van Luik M
      – PersonEntity:
          Name:
            NameFull: Del Nery E
      – PersonEntity:
          Name:
            NameFull: Bellini A
      – PersonEntity:
          Name:
            NameFull: Chua E
      – PersonEntity:
          Name:
            NameFull: Swaak S
      – PersonEntity:
          Name:
            NameFull: Looze EJ
      – PersonEntity:
          Name:
            NameFull: Pietiäinen VM
      – PersonEntity:
          Name:
            NameFull: Turunen LL
      – PersonEntity:
          Name:
            NameFull: Saarela JS
      – PersonEntity:
          Name:
            NameFull: Schueler J
      – PersonEntity:
          Name:
            NameFull: Indersie E
      – PersonEntity:
          Name:
            NameFull: Gürgen D
      – PersonEntity:
          Name:
            NameFull: Scotlandi K
      – PersonEntity:
          Name:
            NameFull: Eggert A
      – PersonEntity:
          Name:
            NameFull: Bouarich-Bourimi R
      – PersonEntity:
          Name:
            NameFull: Bourdeaut F
      – PersonEntity:
          Name:
            NameFull: Zaidi S
      – PersonEntity:
          Name:
            NameFull: Surdez D
      – PersonEntity:
          Name:
            NameFull: Carcaboso ÁM
      – PersonEntity:
          Name:
            NameFull: Geoerger B
      – PersonEntity:
          Name:
            NameFull: Federico A
      – PersonEntity:
          Name:
            NameFull: Kool M
      – PersonEntity:
          Name:
            NameFull: Iddir Y
      – PersonEntity:
          Name:
            NameFull: Saint-Charles A
      – PersonEntity:
          Name:
            NameFull: Saberi-Ansari E
      – PersonEntity:
          Name:
            NameFull: Cavalli F
      – PersonEntity:
          Name:
            NameFull: Gopisetty A
      – PersonEntity:
          Name:
            NameFull: Rief EM
      – PersonEntity:
          Name:
            NameFull: Caron HN
      – PersonEntity:
          Name:
            NameFull: Stancato L
      – PersonEntity:
          Name:
            NameFull: Vassal G
      – PersonEntity:
          Name:
            NameFull: Pfister S
      – PersonEntity:
          Name:
            NameFull: Koster J
      – PersonEntity:
          Name:
            NameFull: Eising S
      – PersonEntity:
          Name:
            NameFull: van Hooff SR
      – PersonEntity:
          Name:
            NameFull: van den Boogaard ML
      – PersonEntity:
          Name:
            NameFull: Schleiermacher G
      – PersonEntity:
          Name:
            NameFull: Molenaar JJ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 10
              M: 01
              Text: 2026 Jan 10
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-print
              Value: 2397-768X
          Numbering:
            – Type: volume
              Value: 10
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: NPJ precision oncology
              Type: main
ResultId 1