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Synergistic effects of gentamicin, levofloxacin, and cefotaxime against Aeromonas salmonicida: In vitro and In vivo evaluation.

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Title: Synergistic effects of gentamicin, levofloxacin, and cefotaxime against Aeromonas salmonicida: In vitro and In vivo evaluation.
Authors: Wang X; College of Life and Geographic Sciences, Key Laboratory of Biological Resources and Ecology of Pamirs Plateauin Xinjiang Uygur Autonomous Region, Kashi University, Kashi 844000, China; Helmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, China., Zhong L; Institute of Synthetic Biology Industry, Hunan University of Arts and Science, Changde, Hunan 415000, China.; Shenzhen Key Laboratory of Genome Manipulation and Biosynthesis, Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China. Electronic address: linzhongxavier@foxmail.com., Purushothaman B; Department of Biochemistry, Sri Venkateshwaraa Medical College and Hospital, Redhills, Chennai, India., Zhang Y; Institute of Synthetic Biology Industry, Hunan University of Arts and Science, Changde, Hunan 415000, China.; Helmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, China; Yuelushan Laboratory, Changsha, Hunan 410128, China., Tu Q; Institute of Synthetic Biology Industry, Hunan University of Arts and Science, Changde, Hunan 415000, China.; Helmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, China; Yuelushan Laboratory, Changsha, Hunan 410128, China. Electronic address: tqiang@sdu.edu.cn., Boopathi S; Institute of Synthetic Biology Industry, Hunan University of Arts and Science, Changde, Hunan 415000, China.. Electronic address: boopathiseenivasan@gmail.com.
Source: Bioorganic chemistry [Bioorg Chem] 2026 Mar; Vol. 170, pp. 109485. Date of Electronic Publication: 2026 Jan 08.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Synergistic effects of gentamicin, levofloxacin, and cefotaxime against Aeromonas salmonicida: In vitro and In vivo evaluation.
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  Data: <searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; College of Life and Geographic Sciences, Key Laboratory of Biological Resources and Ecology of Pamirs Plateauin Xinjiang Uygur Autonomous Region, Kashi University, Kashi 844000, China; Helmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, China.<br /><searchLink fieldCode="AU" term="%22Zhong+L%22">Zhong L</searchLink>; Institute of Synthetic Biology Industry, Hunan University of Arts and Science, Changde, Hunan 415000, China.; Shenzhen Key Laboratory of Genome Manipulation and Biosynthesis, Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China. Electronic address: linzhongxavier@foxmail.com.<br /><searchLink fieldCode="AU" term="%22Purushothaman+B%22">Purushothaman B</searchLink>; Department of Biochemistry, Sri Venkateshwaraa Medical College and Hospital, Redhills, Chennai, India.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Institute of Synthetic Biology Industry, Hunan University of Arts and Science, Changde, Hunan 415000, China.; Helmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, China; Yuelushan Laboratory, Changsha, Hunan 410128, China.<br /><searchLink fieldCode="AU" term="%22Tu+Q%22">Tu Q</searchLink>; Institute of Synthetic Biology Industry, Hunan University of Arts and Science, Changde, Hunan 415000, China.; Helmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, China; Yuelushan Laboratory, Changsha, Hunan 410128, China. Electronic address: tqiang@sdu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Boopathi+S%22">Boopathi S</searchLink>; Institute of Synthetic Biology Industry, Hunan University of Arts and Science, Changde, Hunan 415000, China.. Electronic address: boopathiseenivasan@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%221303703%22">Bioorganic chemistry</searchLink> [Bioorg Chem] 2026 Mar; Vol. 170, pp. 109485. <i>Date of Electronic Publication: </i>2026 Jan 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1303703 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2120 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200452068%22">00452068 </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bioorg.2026.109485
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              Text: 2026 Mar
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