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Targeted CRISPR knockout screening identifies known and novel chemogenomic interactions between DNA damaging agents and DNA repair genes.

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Title: Targeted CRISPR knockout screening identifies known and novel chemogenomic interactions between DNA damaging agents and DNA repair genes.
Authors: Heer CD; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States., Elia JL; Department of Pathology, Yale University, New Haven, CT 06510, United States., Menon V; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States., Johnson SS; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States., Arbelaez SR; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States., Friedman S; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States., Lopez-Giraldez F; Department of Genetics, Yale University, New Haven, CT 06510, United States., Sundaram RK; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States., Herzon SB; Department of Chemistry, Yale University, New Haven, CT 06510, United States., Bindra RS; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States.; Department of Pathology, Yale University, New Haven, CT 06510, United States., Gueble SE; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States.; Department of Pathology, Yale University, New Haven, CT 06510, United States.
Source: NAR cancer [NAR Cancer] 2026 Jan 09; Vol. 8 (1), pp. zcaf052. Date of Electronic Publication: 2026 Jan 09 (Print Publication: 2026).
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101769553 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8674 (Electronic) Linking ISSN: 26328674 NLM ISO Abbreviation: NAR Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeted CRISPR knockout screening identifies known and novel chemogenomic interactions between DNA damaging agents and DNA repair genes.
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  Data: <searchLink fieldCode="AU" term="%22Heer+CD%22">Heer CD</searchLink>; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Elia+JL%22">Elia JL</searchLink>; Department of Pathology, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Menon+V%22">Menon V</searchLink>; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Johnson+SS%22">Johnson SS</searchLink>; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Arbelaez+SR%22">Arbelaez SR</searchLink>; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Friedman+S%22">Friedman S</searchLink>; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Lopez-Giraldez+F%22">Lopez-Giraldez F</searchLink>; Department of Genetics, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Sundaram+RK%22">Sundaram RK</searchLink>; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Herzon+SB%22">Herzon SB</searchLink>; Department of Chemistry, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Bindra+RS%22">Bindra RS</searchLink>; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States.; Department of Pathology, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Gueble+SE%22">Gueble SE</searchLink>; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, United States.; Department of Pathology, Yale University, New Haven, CT 06510, United States.
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  Data: <searchLink fieldCode="JN" term="%22101769553%22">NAR cancer</searchLink> [NAR Cancer] 2026 Jan 09; Vol. 8 (1), pp. zcaf052. <i>Date of Electronic Publication: </i>2026 Jan 09 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101769553 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2632-8674 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226328674%22">26328674 </searchLink><i>NLM ISO Abbreviation: </i>NAR Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1093/narcan/zcaf052
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              Text: 2026 Jan 09
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